期刊文献+

白天过度嗜睡患儿的生理学检查方法评估

Evaluation of Physiological Examination Methods for Excessive Daytime Sleepiness in Children
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摘要 目的探讨多导睡眠图(PSG)和白天多次小睡潜伏期试验(MSLT)2种生理学方法对白天过度嗜睡(EDS)患儿的评估。方法对睡眠相关呼吸障碍组、发作性睡病组及特发性嗜睡组共61例不同病因的EDS患儿行整夜PSG和白天MSLT检查。MSLT在PSG结束2~3 h开始第1次MSLT,以后以每2 h行1次检查的间隔依次进行第2-5次试验,检查前1周禁用对睡眠有影响的药物。结果 44例发作性睡病中36例(81.8%)符合MSLT诊断标准;MSLT 2指标中,3组平均睡眠潜伏期比较差异无统计学意义(F=1.348,P>0.05);发作性睡病组入睡期快速眼动睡眠显著高于特发性嗜睡组和睡眠相关呼吸障碍组(F=21.81,P<0.01);PSG指标中总睡眠时间(TST)、睡眠潜伏期、睡眠效率、非快速动眼动睡眠(NREM)2期和3+4期比例、REM比例3组间差异均无统计学意义(Pa>0.05),特发性嗜睡组NREM 1期比例显著低于其他2组(P<0.01),发作性睡病组REM潜伏期显著短于其他2组(Pa<0.01),睡眠相关呼吸障碍组呼吸暂停低通气指数和最低血氧饱和度与其余2组比较差异有统计学意义(Pa<0.01)。结论MSLT/PSG任何单一的方法评价儿童EDS都是片面和不完整的,二者联合可对儿童EDS做出更全面客观的评估。
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2012年第7期529-530,共2页 Journal of Applied Clinical Pediatrics
基金 河南省卫生厅科技攻关计划项目资助(201003071)
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参考文献9

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