精神分裂症患者自测健康状况及相关因素研究

A study on self-rated health condition and related factors in hospitalized patients with shcizophrenia

目的探讨住院精神分裂症患者自测健康状况及其影响因素。方法采用自编一般情况问卷、自测健康状况评定量表(SRHMS)、多伦多述情量表(TAS-26)、自评抑郁量表(SDS)对320例住院的精神分裂症患者(精神分裂症组)与120名健康志愿者(对照组)进行评定,并进行相关与回归分析。结果精神分裂症患者SRHMS总分及因子分显著低于对照组(P<0.05或P<0.01)。SRHMS总分及多个纬度与SDS、TAS-26总分及TAS因子分呈显著相关(P<0.05或P<0.01)。SDS总分、总体疗效、治疗不良反应等依次进入精神分裂症SRHMS总分的回归方程。结论精神分裂症健康状况不良,负性情绪、治疗效果、治疗不良反应等是其健康状况的重要影响因素。

Objective To explore serf-rating health condition and related factors in hospitalized schizophrenia. Methods A total of 320 patients with schizophrenia and 130 healthy controls were assessed with a self-designed general condition questionnaire, Self-rating Health Measurement Scale Version 1.0 （SRHMS） , Toronto Alexithymia Scale （ TAS- 26） and Self-rating Depression Scale and Depression Status Inventory （SDS）. Correlation and regression analysis were carried out. Results Compared with controls, schizophrenic patients showed significantly lower scores in total score and each factor score of SRHMS （P 〈0.05 or P 〈0.01 ）. The total score and most factor scores of SRHMS were significantly corrrelated with the total scores of SDS,TAS-26 and its factors in patients with schizophrenia （P 〈0.05 or P 〈 0.01 ）. The total score of SDS, general therapeutic effect and adverse effect, et al. entered the regression equation by turns for the total socre of SRHMS in patients with schizophrenia. Conclusion Patients with schizophrenia suffered from bad health status. Negative mood, therapeutic efficacy and side effects were responsible for health status in patients with schizophrenia.