三种方法治疗细菌性阴道病的疗效及复发情况分析

Analysis of Efficacy and Relapse of Three Therapeutic Methods for Bacterial Vaginosis

目的分析3种方法治疗细菌性阴道病(BV)的临床效果及复发情况。方法选择在我院门诊就诊的单纯性BV的患者600例,随机分为3组,各200例,A组予复方甲硝唑泡腾片置入阴道深部;B组予乳杆菌活菌胶囊阴道给药;C组先将复方甲硝唑泡腾片置于阴道深部,随后予乳杆菌活菌胶囊置于阴道深部。结果 A、B、C组的总有效率分别为90.0%,88.0%和93.5%。经秩和检验,三组治疗效果无显著性差异(P>0.05)。A、B组的复发率分别为20.88%和20.35%,经比较差异无统计学意义(P>0.05);但C组的复发率明显低于A、B组,差异有统计学意义(P<0.05)。结论复方甲硝唑泡腾片联合乳杆菌活菌胶囊阴道给药治疗BV疗效好,复发率低。

Objective To analyze the efficacy and relapse of 3 therapeutic methods in the treatment of patient with bacterial vaginosis（BV）.Methods 600 outpatients with BV were divided into 3 groups randomly,group A was assigned to receive metronidazole tablets in deep site of vagina;group B was assigned to receive lactabacillus;group C vaginal administration of metronidazole tablets before the lactabacillus was placed in deep site of vagina.Results The clinical efficacy were 90.00% in group A,88.0% in group B and 93.5% in group C.The difference had no statistically significance among three groups（P0.05）.The recurrence rate of group A and B were 20.88% and 20.35% respectively,the difference of which had no statistically significance（P0.05）;however,the recurrence rate of group C was significantly lower than group A and B（P0.05）.Conclusion Metronidazole tablets combined with lactobacillus is effective in treating BV with low recurrence rate.