小儿法洛四联症早期根治术的效果评价

Early radical therapeutic effect evaluation in children with tetralogy of Fallot

目的评价婴幼儿TOF早期根治性治疗术后疗效。方法回顾性分析2007年8月至2010年8月收治的月龄2～36个月TOF婴幼儿88例临床资料,将所有病例,按月龄12个月为界,随机分为A、B组,A组43例,2～12个月,平均(6.5±4.6)个月,B组45例,12～24个月,平均(16.8±6.6)个月。比较不同年龄组手术病死率、围手术期处理、术后并发症及随访结果。结果A组1例(2.3%)死亡,B组8例(17.8%)死亡,2组术后并发症比较差异有统计学意义(P<0.05)。A组术后患儿更多需要升压药维持,但术后呼吸机通气时间、ICU停留时间与B组比较差异无统计学意义(P>0.05)。结论月龄小于12个月婴儿TOFⅠ期根治手术病死率和术后并发症低,早期手术治疗婴儿TOF可降低病死率及减少并发症的发生。

Objective To evaluate the effects of early radical operation after curative treatment of infants with tetralogy of Fallot（TOF）.Methods To retrospectively analyze 88 cases of infants ranging from 2 to 36 months with TOF,from August 2007 to August 2010 in our hospital.The moon＇s age of 12 months was as a boundary and infants were randomly divided into A and B group,with 43 cases in Group A,from 2 to 12 months,and（6.5±4.6） months on average,45 cases in Group B,from 12 to 24 months and（16.8±6.6） months on average.Operation case fatality rate,operation period processing,postoperative complications and follow-up results were compared in different age groups.Results 1 patients（2.3%） in group A died,8 patients（17.8%） in group B died.The difference in postoperative complications of two groups was statistically significant（P0.05）.Group A children were in additional need of vasopressors after operation to maintain,but the difference in postoperative ventilator time and ICU stay was not statistically significant compared with B group（P0.05）.Conclusion Both mortality and incidence of complications in the moon＇s age of 12 months infants with TOF after radical operation are low.Early surgical treatment of infants can reduce the TOF mortality and complications.