张景岳《新方八阵》配伍规律研究

Research on regular pattern of formula compatibility about the New Eight Arrays Formulas written by ZHANG Jing-yue

目的:以张景岳《新方八阵》167首内服方剂为研究对象,用数据挖掘方法探讨张景岳组方用药的规律。方法:基于频繁项集和关联规则分析。结果:通过频繁项集分析发现:出现频数最高的2味中药组合有2组:熟地黄+当归、熟地黄+炙甘草;3味中药组合为熟地黄+当归+炙甘草;4味中药组合为人参+熟地黄+当归+炙甘草。通过关联规则分析,挖掘出关联关系密切的规则30条,其中2味药对15条,3味药团15条。结论:《新方八阵》内服方剂数据挖掘的结果为张景岳学术思想和治病经验的具体体现,对临床组方用药提供了重要的参考价值。

Objective： To New Eight Arrays Formulas 167 formulas for the study,using data mining method to explore regular pattern of Formula compatibility of ZHANG Jing-yue.Methods： Based on the frequent item sets and association rules analysis.Results： Through the analysis of frequent item sets found： The highest frequency of two kinds of Chinese Materia Medica combined are two groups： Radix Rehmanniae Preparata and Chinese Angelica,Radix Rehmanniae Preparata and mix-fried licorice;three kinds of Chinese Materia Medica combined is Radix Rehmanniae Preparata and Chinese Angelica and mix-fried licorice;four kinds of Chinese Materia Medica combined is ginseng and Radix Rehmanniae Preparata and Chinese Angelica and mix-fried licorice.Through the analysis of association rules,to dig out the 30 rules of close association,in which a combination of two Chinese herbs rules 15,a combination of three Chinese herbs rules 15.Conclusion： The result of data mining of traditional Chinese herbal formula（profess to convinced） in New Eight Arrays Formulas written by ZHANG Jing-yue reflects the thinking of ZHANG Jing-yue,s academic and treatment experience,and for clinical prescribing provides an important reference value.