鸟分枝杆菌复合群肺病和脓肿分枝杆菌肺病临床特点的对比研究

Comparison of Clinical Characteristics between Mycobacterium avium- intracellulare Complex and Mycobacterium abscessus Pulmonary Diseases

目的比较鸟分枝杆菌复合群（M．avium-intracellularecomplex，MAC）肺病和脓肿分枝杆菌肺病临床特点的差异。方法回顾性分析18例MAC肺病和9例脓肿分枝杆菌肺病的临床特点。结果MAC肺病以上叶空洞型常见（13／18），脓肿分枝杆菌肺病以结节支气管扩张型常见（8／9）。脓肿分枝杆菌肺病双肺微结节、树芽征和多发支气管扩张较MAC肺病常见（P〈0．05），MAC肺病的上叶空洞较脓肿分枝杆菌肺病常见（P〈O．05）。结论MAC肺病和脓肿分枝杆菌肺病在许多方面特点类似，但是双肺微结节、树芽征和多发支气管扩张多见于脓肿分枝杆菌肺病，上叶空洞则多见于MAC肺病。

objective To compare the clinical characteristics of nontuberculous mycobacterial pulmonary diseases caused by M. avium- intracellulare complex （MAC） and Mycobacterium abscessus. Methods We retrospectively analyzed the clinical characterisctics of 18 patients with MAC and 9 patients with M.abscessus pulmonary diseases. Results The upper lobe cavitary lesion was more frequently observed in the MAC group （13/18） , whereas the nodular bronchiectatic lesion was more common in the M.abscessus group （3/9）. Compared to the MAC pulmonary diseases, bilateral micronodules, tree-in-bud sign and multiple bronchiectesis were more common in M.abscessus group （P〈0.05） . In addition, the upper lobe cavities were more common in MAC pulmonary diseases compared with the M.abscessus group （P〈0.05）. Conclusion There are similar findings in common clinical characteristics of MAC and the M.abscessus pulmonary diseases. However, bilateral mieronodules, tree-in-bud sign and multiple bronchiectesis are more frequently seen in M.abscessus than MAC pulmonary diseases, and the upper lobe cavities are more frequently seen in MAC than M.abscessas pulmonary diseases.