肺癌患者癌因性疲乏与生活质量的相关性研究

The correlation between cancer the related fatigue and life quality among lung cancer patients

目的探讨肺癌患者癌因性疲乏（CRF）的相关因素及其对生活质量的影响。方法选取98例肺癌住院患者为研究对象，采用一般资料调查表、Piper疲乏修正量表（Revise—Pfs）、癌症生命质量评定量表（QLQ-C30）对其进行问卷调查，了解肺癌患者疲乏程度及生活质量水平，分析其相关因素。结果98例肺癌患者中18．4％轻度疲乏，59．2％中度疲乏，22．4％重度疲乏；疲乏总分（5．18±1．61）分，行为疲乏（5．66±2．22）分，情感疲乏（5．36±2．26）分，躯体疲乏（5．69±1．97）分，认知疲乏（4．11±1．81）分；患者整体健康状况得分（51．02±19．67）分属于中等水平，功能维度中情感功能（80．95±16．01）分，认知功能（81．97±19．98）分得分较高，症状条目中经济困难（58．50±27．52）分得分较高；是否有宗教信仰及不同病程的患者癌因性疲乏总分比较差异均有统计学意义（t=5．979，F=3．251；P〈0．05）；而不同职业状况、年龄、临床分期患者在QLQ—C30个别维度中也存在差异；患者疲乏总分与整体健康状态及疲乏症状均相关，差异均有统计学意义（r分别为-0．425，0．303；P〈0．01）。结论癌因性疲乏是影响肺癌患者生活质量的重要因素，临床上应提供相应的护理干预缓解患者疲乏程度，提高癌症患者的生活质量。

Objective To explore the relevant factors of cancer-related fatigue among lung cancer patients and the influence for their life quality. Methods Totals of 98 patients with tung cancer were selected and investigated with demographic information , Piper＇ s Revise fatigue scale （Revise-Pfs） to assessed the fatigue degree of lung cancer patients ,Life Quality scale of cancer patients（QLQ-C30） to measured the life quality ,then relevant factors were analysed. Results Among 98 cases,mild fatigue cases was 18.4%, moderate degree fatigue cases was 59.2% ,severe fatigue cases was 22.4%. Fatigue score was（5.18± 1.61 ）, behavioral fatigue score was （5.66± 2.22）, emotional fatigue score was （5.36± 2.26）, physical fatigue score was （ 5.69 ±1.97 ）, cognitive fatigue score was （4.11 ± 1.81 ）. The health score of patients was （51.02 ±19.67）which had a medium level, mental function score（80.95 ± 16.01 ） and cognitive function score（81.97 ± 19.98） was the higher dimension score of function dimension,financial difficulty score （58.50 ± 27.52）was the highest term score of symptom dimension. There were significant difference on the incidence cancer-related fatigue score among patients with different disease course and whether had religion（t =5. 979,F =3. 251;P 〈0. 05）. Patients with occupational status, age ~d clinical stage had different score of some dimensions in QLQ-C30, and patients＇ fatigue total score correlated with total health status and fatigue symptom （ r = - 0. 425,0. 303, respectively; P 〈 0. 01 ）. Conclusions Cancer related fatigue of patients with lung cancer is the important factor influencing patients＇ life quality, so it is important to provided relative nursing intervention to relief patients＇ fatigue and to improve the quality of life of them.