慢性肾脏病病人发生左心室肥大的临床分析

The Prevalence Of Left Ventricuar Hypertrophy In Patients With Chronic Kidney Disease

目的:通过心脏超声分析慢性肾脏病(chronic kidney disease,CKD)病人发生左心室肥大(left ventricular hypertrophy,LVH)的临床情况。方法:入选的146例病人根据肾小球滤过率(glomerularfiltration rate GFR)分为3组:早中期组[GFR>30ml(/min.1.73m2)]、中晚期非透析组[GFR≤30ml(/min.1.73m2)]、透析组。146例病人均行心脏超声检查,并对检查结果进行临床分析。结果:146例病人,其中118例(81.2%)存在LVH。在41例早中期组病人,即有24例(58.6%)发生LVH,中晚期非透析组和透析组93例病人(88.5%)发生LVH。LVPW、LVST、TLVMI及LVH随肾功能下降而增加,差异有统计学意义(P<0.05)。结论:CKD早中期阶段即有较高的LVH发生率,随着肾功能下降有逐渐增高趋势。

Objective to evaluate the prevalence of left ventricular hypertrophy（LVH） in inpatients with chronic kidney disease（CKD）. Methods We Recruited 146 inpatients with chronic kidney disease （CKD）,and assigned them based on GFR into early-medium stage group （GFR〉30ml/min/1.73mZ）,medium-advanced stage without dialysis group （GFR〈30ml/min/1.73m2）, or dialysis group. LVDd,LVDs,LAD, LVPWT,LVST and LVMI were measured by cardiac ultrasonography imaging. Results A total of 146 cases were enrolled,Cardiac ultrasonog- raphy was performed in 146 patients,of which 118 cases（81.2% ）showed left vehicular hypertrophy（LVH）. In the 41 eases in early-medium stage group,24 cases（58.6%）already had LVH. In the 93 cases（88.5%） medium-advanced stage without dialysis group or dialysis group had LVH.LVPW,LVST,TLVMI LVH with the deterioration of CKD had larger LVPW,LVST,TLVMI and LVH （P〈0.05）. Conclusion LVH occurs earlier even in the early-medium stage of the CKD.The prevalence rate of LVH is higher with the deterioration of CKD.