摘要
目的探讨脂质代谢在子痫前期发病中的作用。方法用酶法检测28例重度子痫前期产妇(子痫前期组)和30例健康孕足月产妇(对照组)的外周血甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-c)、高密度脂蛋白胆固醇(HDL-c)水平;用油红染色法检测10例子痫前期组和10例对照组胎盘组织中脂质水平。结果子痫前期组外周血中TG、TC、LDL-c水平明显高于对照组(P<0.05),HDL-c水平明显低于对照组(P<0.05)。子痫前期胎盘组织中的脂质水平明显高于对照组(P<0.05)。结论子痫前期产妇存在明显的高脂质代谢异常。异常脂质代谢在子痫前期发病中起着一定的诱导作用。
Objective: To discuss the effectiveness of lipid in the pathogenesis of preeclampsia.Methods: 28 cases of severe preeclampsia and 30 normal pregnant women were selected in this study.The peripheral blood serum were analyzed for the levels of triglyceride(TG),total cholesterol(TC),low density lipoprote cholesterol(LDL-c),high density lipoprote cholesterol(HDL-c) by enzymid methods.The lipid levels of placentas with 10 cases of severe preeclampsia and 10 normal pregnant women were analyzed by oil red staining.Results: Compared with normal pregnant women,the levels of TG,TC,LDL-c were increased significantly,the levels of HDL-c was decreased in severe preeclampsiawomen(P〈0.05).The lipid was generally deposited in placentas in severe preeclampsia women.Conclusion: The abnormal metabolism of hyperlipermia were found significantly in severe preeclampsia.The abnormal lipid metabolism possibly was a induction in the pathogenesis of preeclampsia.
出处
《中国优生与遗传杂志》
2012年第3期27-28,14,共3页
Chinese Journal of Birth Health & Heredity
关键词
子痫前期
外周血
胎盘组织
脂质代谢
Preeclampsia
Peripheral blood serum
Placenta
Lipid metabolism