川西獐牙菜的化学成分、药理作用和临床应用研究进展

Research progress on chemical constituents,pharmacological actions,and clinical applications of Swertia mussotii

川西獐牙菜是我国传统藏药"藏茵陈"原植物之一,含有呫吨酮、环烯醚萜苷、三萜等化学成分,具有保肝、抑菌等药理作用。其临床应用主要为各型肝炎的治疗,已被开发为多种剂型的成药,该植物其他方面的应用还有待于进一步研究。对该植物的化学成分、药理作用和临床应用研究进展做一综述,以期为开发和利用川西獐牙菜提供参考。

Swertia mussotii has been used as one of the original plants of Tibetan medicine ＂Zangyinchen＂.It contains xanthones,secoiridoid glycosides,and triterpenoid saponins,and so on,with hepayoprotective,antibacterial activity,etc.In the clinical application,the plant maily used for various types of hepatitis and has been developed in various dosage forms.Other applications of the plant remains to be further studied.This paper reviewed the progress of research in chemical constituents,pharmacological actions,and clinical applications of S.mussotii it,which will offer references for further study and application.