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CT引导下PVP联合^(125)I粒子椎弓根植入治疗脊柱转移瘤(附25例报告) 被引量:4

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摘要 目的观察CT引导下经皮椎体成形术(PVP)联合放射性125I粒子椎弓根植入治疗脊柱转移瘤的临床疗效。方法脊柱转移瘤患者25例(共30个椎体),采用PVP治疗,在CT引导下利用放射治疗计划系统(TPS),经病变椎体两侧椎弓根精确植入125I粒子。CT扫描观察骨水泥有无明显渗漏,观察粒子在病椎内的总体分布情况及粒子有无遗漏。结果 25例中,共注射椎体30个,每个椎体植入125I粒子2~4枚。患者术后均未出现神经症状加重,粒子分布均基本符合设计要求,无丢失、遗漏。1例术后出现发热(39℃),对症治疗后恢复。所有患者术后腰背部疼痛均明显减轻或消失,均未出现神经损伤等并发症及放射相关不良反应。术后随访6~20个月,其中12例因肿瘤转移、脏器衰竭于术后6~14个月死亡,余13例目前仍存活,生活质量明显改善。结论 CT引导下PVP联合125I粒子椎弓根植入治疗脊椎转移瘤安全、可靠,疗效较好。
出处 《山东医药》 CAS 2012年第10期30-31,共2页 Shandong Medical Journal
基金 河北省卫生厅医学科学研究重点课题计划(07307) 河北省科技厅科技支撑课题项目(052761164)
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同被引文献34

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