基于聚类分析的血管性痴呆中医用药分析

Analysis of TCM Drug in Vascular Dementia Based on Cluster Analysis

通过对近30年生物医学期刊有关中医治疗血管性痴呆文献的处方录入,对其用药进行频数分析、聚类分析,探索中医治疗血管性痴呆的常用药物和配伍规律。频数分析结果显示,菖蒲、川芎、黄芪、何首乌、远志、丹参、当归、枸杞子、郁金、水蛭、淫羊藿等为常用药物。聚类分析结果显示了本病治疗的用药规律。用统计学方法定量分析中药治疗血管性痴呆的用药处方规律,可更好的指导临床,同时也是血管性痴呆证候规范化研究的一部分。

These drugs were performed by the frequency analysis and the cluster analysis through inputting pre- scriptions in the vascular dementia of recent 30 years in order to explore the commonly used medicine and com- patibility law of traditional Chinese medicine. From the frequency analysis, there were some drugs used commonly including Drug Sweettlag Rhizome ,Szeehuan Lovage Rhizome, Membranous Milkvetch Root,Polygonum muhiflo- rum, Thinleaf Milkwort Root-bark, Danshen Root, Chinese Angelica, Barbary Wolfberry Fruit, Turmeric Root-tu- ber,Leech,Epimedium Herh,etc. Meanwhile,the using regularity was showed by the cluster analysis. The regu- larity of vascular dementia drug which was analysed by statistical methods was one of the study on syndrome stan- dard in the vascular dementia.