医院抗骨质疏松药物用药趋势分析与合理应用评价

Trend Analysis on Anti-Osteoporosis Drugs Use in Our Hospital and Reasonable Application Evaluation

目的分析医院抗骨质疏松药的应用情况,为临床合理使用提供参考。方法根据抗骨质疏松药的不同结构及作用机制进行分类,采用世界卫生组织推荐的限定日剂量、用药频度分析法对2008年至2010年抗骨质疏松药销售金额、用药频度及日均费用等进行回顾性分析。结果抗骨质疏松药中,碳酸钙片迪巧和钙尔奇-D用药频度最高,双膦酸盐类增长迅速;唑来磷酸(择泰)日均费用最高。结论抗骨质疏松药物应用情况调查,对于促进合理应用及临床监护具有重要意义。

Objective To understand the use status of anti- osteoporosis drugs in our hospital to provide reference for clinical rational use. Methods The classification was conducted according to different structures and mechanisms of anti- osteoporosis drugs. The defined daily dose（DDD） frequency analysis recommended by WHO was adopted to retrospectively analyze the sale amounts, use frequency and daily drug costs of anti- osteoporosis drugs in our hospital from August 2008 to July 2010. Results Among anti- osteoporosis drugs, Calcium Carbonate Tablets, D- Cal and Caltrate- D had highest DDDs. Bisphosphonates were increased rapidly. Zometa had highest aver- age daily costs. Conclusion The investigation of anti- osteoporosis drugs use has important significance to promote their rational use and clinical monitoring.