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大肠腺癌中E2F1和p16蛋白的表达与预后的关系 被引量:2

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摘要 肠道恶性肿瘤以腺癌最常见,是消化道最常见的恶性肿瘤之一,大肠癌的发生发展涉及多种因素的作用,其中包括与细胞周期相关基因的激活及抑癌基因的失活等,E2F1转录因子为细胞周期的正性调节因子,在细胞周期的调控中起着重要的作用,p16为细胞周期的负性调控因子,对细胞周期的进展起着负性调节作用。
作者 冀建波
出处 《山西医药杂志(上半月)》 CAS 2012年第4期342-343,共2页 Shanxi Medical Journal
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