冠心病无症状和有症状心肌缺血患者双嘧达莫试验的对比分析

Comparative Analysis of Dipyridamole Test between Silent Myocardial Ischemia and Myocardial Ischemia Patients

目的 :认识冠心病无症状心肌缺血病情的隐蔽性及潜在危险性 ,提高其诊断率 ,降低致死率。方法 :根据运动试验、HOLTER、心电图将 12 0例冠心病患者分为无症状组 (6 7例 )及有症状组 (5 3例 ) ,通过双嘧达莫试验进行对比分析。结果 :试验中有症状组出现典型心绞痛率显著高于无症状组 (χ2 =7.48,P <0 .0 1) ,而两组心肌缺血程度 (t=0 .0 86 ,P >0 .0 5 )及阳性率 (χ2 =1.82 ,P >0 .0 5 )无明显差异。结论 :无症状心肌缺血因较少临床症状常被忽视 ,但其心肌缺血程度并不亚于有症状者 ,故应引起高度重视 。

To better understand the potential danger of silent myocardial ischemia (SMI) of coronary artery disease,120 patients with coronary artery disease were divided into two groups:SMI group(67 cases) and myocardial ischemia (MI) group (53 cases) on the basis of results of exercise test,Holter and electrocardiograms.The two groups were observed and compared after Dipyridamole Test and results showed that the incidence of typical angina pectoris in MI group was significantly higher than that in SMI grop( χ 2= 7.48 ; P< 0.01 ),but the degree of the myocardial ischemia( t = 0.086 , P>0.05 ) and the positive rate( χ 2= 1.82; P> 0.05 ) between the two groups were not significantly different.It was concluded that SMI was usually ignored owing to little clinical presentation,but its degree of myocardia ischemia was no less than that in MI.So more attentions should be paid to SMI and Dipyridamole Test has been very helpful in the research and prevention of SMI.