期刊文献+

补体调控异常相关的溶血尿毒综合征 被引量:2

原文传递
导出
摘要 溶血尿毒综合征(hemolytic uremic syndrome,HUS)是儿童急性肾衰竭最常见的原因,属于全身性血栓性微血管病,临床以微血管病性溶血性贫血、血小板减少和急性肾衰竭为特征。以往根据有无腹泻症状将HUS分为腹泻后HUS(D HUS,即典型HUS)和非腹泻后HUS(D—HUS,即非典型HUS)。其中非典型HUS占儿童HUS的5%~10%,
作者 管娜
出处 《中华儿科杂志》 CAS CSCD 北大核心 2012年第4期286-289,共4页 Chinese Journal of Pediatrics
  • 相关文献

参考文献39

  • 1Besbas N,Karpman D,Landau D. A classification of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura and related disorders[J].Kidney International,2006.423-431.
  • 2Waters AM,Licht C. aHUS caused by complement dysregulation:new therapies on the horizon[J].Pediatric Nephrology,2011.41-57.
  • 3Keir L,Coward RJ. Advances in our understanding of the pathogenesis of glomerular thrombotic microangiopathy[J].Pediatric Nephrology,2011.523-533.doi:10.1007/s00467-010-1637-4.
  • 4Kavanagh D,Goodship T. Genetics and complement in atypical HUS[J].Pediatric Nephrology,2010.2431-2442.
  • 5Venables JP,Strain L,Routledge D. Atypical haemolytic uraemic syndrome associated with a hybrid complement gene[J].PLOS MEDICINE,2006.e431.doi:10.1371/journal.pmed.0030431.
  • 6Bienaime F,Dragon-Durey MA,Regnier CH. Mutations in components of complement influence the outcome of factor Ⅰ-associated atypical hemolytic uremic syndrome[J].Kidney International,2010.339-349.doi:10.1038/ki.2009.472.
  • 7Chan MR,Thomas CP,Torrealba JR. Recurrent atypical hemolytic uremic syndrome associated with factor Ⅰ mutation in a living-related renal transplant recipient[J].American Journal of Kidney Diseases,2009,(2):321-326.doi:10.1053/j.ajkd.2008.06.027.
  • 8Cruzado JM,de Cordoba SR,Melilli E. Successful renal transplantation in a patient with atypical hemolytic uremic syndrome carrying mutations in both factor Ⅰ and MCP[J].American Journal of Transplantation,2009.1477-1483.doi:10.1111/j.1600-6143.2009.02647.x.
  • 9Esparza-Gordillo J,Jorge EG,Garrido CA. Insights into hemolytic uremic syndrome:segregation of three independent predisposition factors in a large,multiple affected pedigree[J].Molecular Immunology,2006.1769-1775.
  • 10Kavanagh D,Richards A,Noris M. Characterization of mutations in complement factor Ⅰ (CFI) associated with hemolytic uremic syndrome[J].Molecular Immunology,2008.95-105.doi:10.1016/j.molimm.2007.05.004.

同被引文献47

  • 1Waters AM,Licht C. Ahus caused by complement dysregulation:new therapies on the horizon [J]. Pediatr Nephrol, 2011,26:41-57.
  • 2Moore I, Strain L, Pappworth I,et al. Association of factor Hautoantibodies with deletions of CFHR1,CFHR3 , CFHR4, andwith mutations in CFH,CFI,CD46,and C3 in patients withatypical hemolytic uremic syndrome [J] . Blood, 2010,115:379-387.
  • 3Ariceta G, Besbas N, Johnson S, et al. European Paediatric StudyGroup for HUS. Guideline for the investigation and initial therapyof diarrhea-negative hemolyticuremic syndrome [J] . PediatrNephrol, 2009, 24: 687-696.
  • 4Filler G,Radhakrishnan S,Strain L,et al. Challenges in themanagement of infantile factor H associated hemolytic uremicsyndrome[J]. Pediatr Nephrol, 2004, 19: 908-911.
  • 5Dragon-Durey MA,Loirat C,Cloarec S,et al. Anti-Factor Hautoantibodies associated with atypical hemolytic uremic syndrome[J]. J Am Soc Nephrol, 2005,16: 555-563.
  • 6Dragon-Durey MA, Sethi SK, Bagga A, et al. Clinical features ofanti-factor H autoantibody-associated hemolytic uremic syndrome[J]. J Am Soc Nephrol, 2010, 21:2180-2187.
  • 7Boyer 0,Balzamo E, Charbit M, et al. Pulse cyclophosphamidetherapy and clinical remission in atypical hemolytic uremicsyndrome with anti-complement factor H autoantibodies [J]. Am JKidney Dis, 2010, 55: 923-927.
  • 8Sellier-Leclerc AL, Fremeaux-Bacchi V, Dragon-Durey MA, etal. Differential impact of complement mutations on clinicalcharacteristics in atypical hemolytic uremic syndrome[J]. J AmSoc Nephrol, 2007,18: 2392-2400.
  • 9Huang Y,Liu Z,Huang H,et al. Effects of mycophenolic acid onendothelial cells [J] . Int Immunopharmacol, 2005,5: 1029-1039.
  • 10Loirat C, Fr6meaux-Bacchi V. Atypical hemolytic uremic syndrome [J]. Orphanet J Rare Dis, 2011, 6:60.

引证文献2

二级引证文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部