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635/808双波长低强度照射对术后创口愈合的影响(英文) 被引量:2

Effects of Low Intensity Laser Irradiation with Combination of 635 and 808 Nanometers on Surgery Wound Healing
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摘要 本文通过评估635/808双波长低强度激光照射对术后病人创口愈合的影响,以给临床应用提供病例参考。随机选取外科手术治疗的非恶性肿瘤患者60例,试验组和对照组各30例。试验组使用635nm/808nm双波长激光辅助切口治疗,对照组以波长635nm的He-Ne激光辅助治疗。激光器发出两路激光对受试者切口部位进行照射治疗,一路波长为(635±5)nm,光功率密度1~6.5mW/cm2,另外一路波长为(808±5)nm,光功率密度为11~32mW/cm2。激光照射治疗开始于手术结束24h之后,每天一次,每次照射15min,至治疗终点(出院或切口愈合拆线),双波长激光器最大功率密度控制在40mW/cm2以下(可调节),最大能量密度在36J/cm2以下(可调节)。He-Ne激光器输出功率最大为100mW,每天一次,每次照射15min,至治疗终点(出院或切口愈合拆线)。试验表明,635/808双波长低照度照射能够促进创口愈合,治疗效果好于He-Ne激光器。 In order to provide a reference for clinical applications,effects of Low Intensity Laser Irradiation(LILI) with combination of 635/808nm on cutaneous wound healings are evaluated.Non-surgical treatment of 60 patients with malignant tumors,the test group and control group of 30 cases is randomly selected.The incision site of patients has been irradiated with laser,which generated two lasers.One was red laser with wavelength at 635 ± 5nm and power density at 1~6.5 mW/cm^2;the other was infrared laser with wavelength at 808 ± 5nm and power density at 11~32 mW/cm^2.Laser treatment was started 24 hours after the end of surgery,each Days once every 15 minutes exposure to treatment endpoint.He-Ne laser treatment began 24 hours after the end of surgery,day 1,each exposure 15 minutes,until the end of treatment(hospital or wound healing stitches).The result shows that LILI with the combination of 635/808 nm could improve cutaneous wound healings of patients significantly rather than using He-Ne laser.
出处 《光电工程》 CAS CSCD 北大核心 2012年第4期121-124,共4页 Opto-Electronic Engineering
关键词 低照度激光照射 635nm/808nm 创口愈合 HE-NE激光器 LILI 635/808 nm wound healing He-Ne laser
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参考文献14

  • 1Mester E,Spiry T,Szende B,et al.Effect of laser rays on wound healing[J].Am J Surg(S0037-945X),1971,122(4):532-535.
  • 2Mester E,Korenyi-Both A,Spiry T,et al.The effect of laser irradiation on the regeneration of muscle fibers(preliminary report)[J].Z Exp Chir(S0323-5580),1975,8(4):258-262.
  • 3李成,李迎新.弱激光生物刺激效应在创伤治疗中的作用[J].医疗卫生装备,2007,28(10):26-28. 被引量:18
  • 4Tiina I Karu.Multiple Roles of Cytochrome c Oxidase in Mammalian Cells Under Action of Red and IR-A Radiation[J].IUBMB Life(S1521-6543),2010,62(8):607–610.
  • 5Kujawa J,Zavodnik L,Zavodnik I,et al.Effect of low-intensity(3.75–25J/cm2)near-infrared(810nm)laser radiation on red blood cell ATPase activities and membrane structure[J].J.Clin.Laser.Med.Surg(S1044-5471),2004,22:11–17.
  • 6Hawkins D H,Abrahamse H.The role of laser fluence in cell viability,proliferation,and membrane integrity of wounded human skin fibroblasts following helium-neon laser irradiation[J].Lasers.Surg.Med(S0196-8092),2006,38:74–83.
  • 7YU W,Naim J O,McGowan M,et al.Photomodulation of oxidative metabolism and electron chain enzymes in rat liver mitochondria[J].Photochem Photobiol(S0031-8655),1997,66:866–871.
  • 8Kassak P,Przygodzki T,Habodaszova D,et al.Mitochondrial alterations induced by 532nm laser irradiation[J].Gen.Physiol Biophys(S0231-5882),2005,24:209–220.
  • 9Bolton P,Young S,Dyson M.The direct effect of 860nm light on cell proliferation and on succinic dehydrogenase activity of human fibroblasts in vitro[J].Journal of Cutaneous Laser Therapy(S1462-883X),1995,7:55–60.
  • 10DUAN R,LIU T C,LI Y,et al.Signal transduction pathways involved in low intensity He-Ne laser induced respiratory burst in bovine neutrophils:a potential mechanism of low intensity laser biostimulation[J].Lasers Surg Med(S0196-8092),2001,29(2):174-178.

二级参考文献18

  • 1Posten William, Wrone David, Dover Jeffrey, et al. Low-Level Laser Therapy for Wound Healing: Mechanism and Efficacy [J]. Dermatologic Surgery,2005,31:334-340.
  • 2Lark J. Wound repair and factors influencing healing [J]. Crit Care Nurs Q,2002,25:1-12.
  • 3Ahuja Shelly, Kothiwale Shaila, Bhat Kishore. Proliferation of the human periodontal ligament fibroblast by laser biostimulation: an in vitro study[J]. Proc SPIE,2006,6140:54-63.
  • 4Alena R A P, Medrado BS, Silvia Regina, et al. Influence of low level laser therapy on wound healing and its biological action upon myofibroblast[J]. Lasers Surg.Med,2003,32:239-244.
  • 5J Ty Hopkins, Todd A McLoda, Jeff G Seegmiller, et al. Low-Level Laser Therapy Facilitates Superficial Wound Healing in Humans: A Triple-Blind, Sham-Controlled Study [J]. Journal of Athletic Training,2004,39(3):223-229.
  • 6G Arun Maiya, Pramod Kumar, Laxmi Rao. Effect of Low Intensity Helium-Neon (He-Ne) Laser Irradiation on Diabetic Wound Healing Dynamics [J]. Photomedicine and Laser Surgery, 2005,23 (2): 187-190.
  • 7Mark d Walker,Shelli Rumpf, G David Baxter, et al. Effect of lowintensity laser irradiation (660 nm) on a radiation-impaired woundhealing model inmurine skin[J]. Lasers Surg. Med,2000,26:41-7.
  • 8C Lucas,M J C van Gemert, R J de Haan. Efficacy of low-level laser therapy in the management of stage Ⅲ decubitus ulcers: a prospective, observer-blinded multicentre randomised clinical trial [J]. Lasers Med Sci,2003,18:72-77.
  • 9Istvan Stadler, Ryan Evans,Brett Kolb, et al. In vitro effects of low-level laser irradiation at 660 nm on peripheral blood lymphocytes[J]. Lasers in Surgery and Medicine,2000,27(3),255-261.
  • 10Ethne L. Lothar Lilge, Tony Mazzulli, et al. Effects of Low-Level Laser Therapy (LLLT) of 810 nm upon in Vitro Growth of Bacteria: Relevance of Irradiance and Radiant Exposure[J]. Journal of Clinical Laser Medicine & Surgery,2003,21(5):283-290.

共引文献17

同被引文献30

  • 1王恩信,荆玉兰,王鹏程,宋艳.NTC热敏电阻器的现状与发展趋势[J].电子元件与材料,1997,16(4):1-9. 被引量:51
  • 2Nikele Nadur-Andrade,Stella K Zamuner,Elaine F Tonio-lo,et al. Analgesic effect of Light-Emitting Diode ( LED)therapy at wavelengths of 635 and 945 nm on bothrops-moojeni venom-induced hyperalgesia[ J]. Photochemistryand Photobiology,2014,90 :207 - 213.
  • 3Hyun-Ju Lim, Man-Seok Bang, Hye-Min Jung, et al. A635 nm Light-Emitting Diode ( LED) therapy inhibitsbone resorptive osteoclast formation by regulating the actincytoskeleton[ J]. Lasers Med Sci ,2014,29 :659 — 670.
  • 4Hideyuki Murayama, Kei Sadakane,Banri Yamanoha, etal. Low-power 808 nm laser orradiation inhibits cell prolif-eration of a human-derived glioblastoma cell line in vitro[J]. Lasers Med Sci,2012,27:87 -93.
  • 5Metin Gungormus,Utkan Akyol. The effect of gallium-alu-minum-arsenide 808 nm low-level laser therapy on healingof skin incisions made using a diode laser[ J]. Photomedi-cine and Laser Surgery, 2009,27 ( 6 ) :895 - 899.
  • 6Jason Z G. Rainbow three-dimensional camera: new con-cept of high-speed three-dimensional vision systems [ J ].Optical Engineering, 1996,35(2) :376 — 383.
  • 7YU Fusheng’SHEN Xiaoqin, LENG Changlin, et al. Finiteelement analysis of laser-diode heat emission and design ofPI fuzzy cooling system[ C]//SPIE,2005,5628.189 -195.
  • 8Rodrigo S M, Cunha A, Pozza D H, et al.. Analysis of the systemic effect of red and infrared laser therapy on wound repair[J]. Photomedicine and Laser Surgery, 2009, 27(6): 929-935.
  • 9Oron U, Ilic S, De Taboada L, et al.. Ga-As (808 nm) laser irradiation enhances ATP production in human neuronal cells in culture[J]. Photomedicine and Laser Surgery, 2007, 25(3): 180-182.
  • 10Ma H, Li Y, Chen H, et al.. Effects of low-intensity laser irradiation on wound healing in diabetic rats[J]. International Journal of Photoenergy, 2012, 2012: 838496.

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