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热灌注TACE、RFA联合^(125)I粒子植入治疗原发性肝癌 被引量:4

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摘要 目的探讨热灌注(hyperthermic perfusion)经肝动脉化疗栓塞(transcatheter arterial chemoembolization,TACE)、射频消融(radiofrequency ablation,RFA)联合125I粒子植入治疗原发性肝癌(primary hepaticalcarcinoma,PHC)的临床应用价值。方法 PHC患者15例,共25个肿瘤灶,病灶大小1~8 cm,所有患者均先进行热灌注TACE,然后在CT引导下RFA及125I粒子植入治疗。本组内放疗处方剂量规定为60 Gy,随访观察疗效及相关并发症。结果随访时间6~40个月(平均26.8个月),全组肿瘤完全坏死率为96%,除1例粒子游走外,未出现其他严重并发症。结论热灌注TACE、RFA联合125I粒子植入治疗PHC,近期疗效明显,可望成为PHC更有效的治疗新模式。
出处 《肝胆胰外科杂志》 CAS 2012年第2期145-147,共3页 Journal of Hepatopancreatobiliary Surgery
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