武汉市成年人骨密度影响因素分析

Analysis on the influencing factors of bone mineral density among adults in Wuhan city

目的探讨武汉市成年人骨密度(Bone mineral density,BMD)的影响因素。方法对379例18岁以上体检者应用双能X线骨密度仪(Dual-energy X-absorptiometry,DEXA)测定正位腰椎骨密度值,并进行问卷调查,对所获资料进行t检验、相关分析及逐步回归分析。结果男性、女性随年龄变化BMD变化规律不同,年龄与BMD呈负相关(r=-0.244,P<0.01),体重与BMD呈正相关(r=0.250,P<0.01),已绝经妇女BMD低于未绝经者(P<0.01),有高血压、冠心病病史者BMD低于未患病者(P<0.01)。结论武汉地区成年人BMD与多种因素有关,年龄、体重、绝经是重要因素,患有高血压、冠心病者应注意防治骨质疏松。

Objective To investigate the influencing factors of bone mineral density（BMD） among adults in Wuhan city.Methods Dual-energy X-absorptiometry（DEXA） were used to measure BMD at the lumbar spine among 379 adults.At the same time a questionnaire was conducted among these subjects.The data was analyzed by independent samples t test,bivariate correlation analysis and stepwise regression analysis.Results With the age changing,males and females tend to have different BMD variation.Age and BMD was found to be negatively correlated（r=-0.244,P0.01）,while body weight and BMD was found to be positively correlated（r=0.250,P0.01）.The BMD from postmenopausal women was obviously lower than those from premenopausal women（P0.01）.The BMD from people with hypertention or conarory heart disease was lower than those without hypertention or conarory heart disease（P0.01）.Conclusion The BMD among adults in Wuhan city is related to many factors,in which the age,body weight and pausimenia are the most important factors.People with hypertention or conarory heart disease should pay more attention to the prevention and treatment of osteoporosis.