中医院尿路感染病原菌的耐药性调查

Antimicrobial resistance of pathogens causing urinary tract infections in traditional Chinese medicine hospital

目的调查医院尿路感染病原菌的分布及耐药性,为临床医师合理使用抗菌药物提供科学依据。方法病原菌培养鉴定按照《全国临床检验操作规程》进行;药敏试验采用CLSI推荐的K-B法进行。结果 259株尿路感染病原菌中,大肠埃希菌居第1位,占55.6%;259株病原菌对抗菌药物产生了不同程度的耐药性,但革兰阳性球菌对糖肽类抗菌药物100.0%敏感;革兰阴性杆菌对碳青霉烯类抗菌药物100.0%敏感。结论中医院尿路感染病原菌的耐药性呈不断增强趋势,临床医师应根据药敏结果针对性用药治疗。

OBJECTIVE To investigate the clinical distribution and antimicrobial resistance of pathogens causing urinary tract infection and provide scientific evidence for clinically reasonable use of antibiotics.METHODS Bacterial culture and identification were performed according to the National Guides to Clinical Laboratory Procedures;drug susceptibility testing was carried out with K-B method recommended by CLSI.RESULTS Among 259 strains of pathogens causing urinary tract infections,Escherichia coli ranked the first,accounting for 55.6%;all of 259 strains of pathogens were resistant to antibiotics in varied degrees,gram-positive cocci were 100.0% sensitive to glycopeptide antibiotics;gram-negative bacilli were 100.0% sensitive to carbopenem antibiotics.CONCLUSION The results showed a growing trend of antimicrobial resistance of the pathogens causing urinary tract infections.The clinician should prescribe the antibiotics for treatment in accordance with the result of drug susceptibility testing.