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血脑屏障细胞组成研究进展 被引量:20

Advance on Study of Cells of Blood-brain Barrier
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摘要 对血脑屏障的细胞组成及其不同的功能进行了文献整理和分析。通过中国知网,PubMed,Elsevier等数据库,检索了近10年来血脑屏障的功能研究,这些功能与之相关的细胞的特殊构造,以及不同细胞之间的相互作用的一个研究近况。通过整理发现组成血脑屏障的细胞包括:基膜、神经元、小的神经胶质细胞、周细胞、星形细胞、内皮细胞组成且每种细胞对血脑屏障功能的形成都有很大贡献。有关血脑屏障的研究目前已成为生命科学领域的研究热点,而有关血脑屏障的细胞组成在近几年也获得一定研究成果。对近年来关于血脑屏障的细胞构成作一整理,以期为血脑屏障的相关研究作参考。 This article summarized and analyzed the cell composition and different functions of blood-brain barrier.Searching recent studies on blood-brain barrier function and particular structure of relative cells and interaction between different cells in 10 years through CNKI,PubMed,Elsevier,etc databases.The blood-brain barrier cells included asement membrane,neuron,small glial cells,pericytes,astrocytes,and endothelial cells etc,each cell played an importantrole in the formation of the blood brain barrier function.The study of the blood-brain barrier has become a key research area.The research work on cell composition of the blood-brain barrier in recent years has achived barrier-related research.
出处 《中国实验方剂学杂志》 CAS 北大核心 2012年第8期281-284,共4页 Chinese Journal of Experimental Traditional Medical Formulae
基金 国家自然科学基金青年基金项目(81001651) 江苏省针药结合省部共建教育部重点实验室开放性研究课题(KJA200905)
关键词 血脑屏障 功能 细胞 研究进展 blood-brain barrier function cell research progress
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参考文献45

  • 1Lee S W,Kim W J,Park J A. Blood-brain barrier interfaces and brain tumors[J].Archives of Pharmacal Research,2006,(4):265.doi:10.1007/BF02968569.
  • 2Pardridge W M. Blood-brain barrier biology and methodology[J].Neurovirol,1999.556.
  • 3Marchi N,Cavaglia M,Fazio V. Peripheral markers of blood-brain barrier damage[J].Clin Chim Acts,2004.1.
  • 4Zozulya A,Weidenfeller C,Galla H J. Pericyteendothelial cell interaction increases MMP-9 secretion at the blood-brainbarrier in vitro[J].Brain Research,2008.1.doi:10.1016/0006-8993(80)90002-5.
  • 5Yurchenco P D,Schittny J C. Molecular architecture of basement membrane[J].Federation of America Societies for Experimental Biology Journal,1990,(01):577.
  • 6Hamann G F,OkadaY,Fit ridge R. Microvascular basal lamina antigens disappear during crebral ischemia and reperfusion[J].Stroke,1995,(02):120.
  • 7Carvey P M,Hendey B,Monahan A J. The blood-brain barrier in neurodegenerative disease:a rhetorical perspective[J].Neurochem,2009,(2):291.doi:10.1111/j.1471-4159.2009.06319.x.
  • 8Weiss N,Miller F,Cazaubon S. Theblood-brain barrier in brain homeostasis and neurological diseases[J].Biochem Biophys Acts,2009.842.
  • 9Hawkins B T,Davis T P. The blood-brain-barrier/neurovascular unit in health and disease[J].Pharmacol Rey,2005.173.
  • 10Zlokovic B V. Theblood-brain-barrier in health and chronic neuron degenerative disorders[J].Neuron,2008,(2):178.doi:10.1016/j.neuron.2008.01.003.

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