摘要
目的:研究牻牛儿苗药材的质量控制方法。方法:采用HPLC法建立牻牛儿苗药材的HPLC指纹图谱,收集不同产地的23批样品进行测定,并使用聚类分析和主成分分析对指纹图谱进行模式识别研究。结果:根据主成分分析和聚类分析结果,筛选14批样品建立指纹图谱共有模式。结论:该方法可用于牻牛儿苗质量控制及综合评价。
Objective:To establish a method for quality control of Erodium stephanianum Willd.Methods:An high performance liquid chromatographic method was developed to establish fingerprint of Erodium stephanianum Willd.,and 23 samples of wild and cultivated from various places had been analyzed.Cluster analysis and principal component analysis(PCA) were applied to study HPLC fingerprint and chemical pattern recognition method.Results:14 samples were selected to establish the common pattern of the fingerprint on the basis of the result of cluster analysis and PCA.Conclusion:The method provides an academic reference for the quality control of Erodium stephanianum Willd..
出处
《药物分析杂志》
CAS
CSCD
北大核心
2012年第4期612-615,共4页
Chinese Journal of Pharmaceutical Analysis
基金
辽宁省教育厅项目(2009A498)
关键词
牻牛儿苗
指纹图谱
没食子酸
原儿茶酸
柯里拉京
鞣花酸
主成分分析
聚类分析
Erodium stephanianum Willd.
fingerprint
gallic acid
protocatechuic acid
corilagin
ellagic acid
principal component analysis(PCA)
cluster analysis