眼针对肠易激综合征患者血清5-羟色胺水平的影响

Effect of Eye Acupuncture on Serum 5-hydroxytryptamine Levels in Patients with Irritable Bowel Syndrome

目的观察眼针对肠易激综合征患者血清中5-HT含量的影响,探究眼针治疗肠易激综合征机理。方法选取2008年1月至2010年12月符合并接受眼针治疗肠易激综合征研究的60例患者,分别于治疗前和治疗后空腹抽取静脉血8 mL离心并冷藏,于疗程前后分别做一次免疫学指标定量检测。结果眼针治疗后5-HT含量[(267.28±105.74)mol/L]明显低于治疗前[(313.07±110.63)mol/L],治疗前后比较差异有统计学意义(P<0.05)。结论眼针通过对5-HT含量的降低对腹泻型肠易激综合征起到治疗作用,揭示了其治疗肠易激综合征的部分生物学机制。

Objective To investigate the effect of eye acupuncture on serum 5-HT content in patients with irritable bowel syndrome and explore the mechanism of eye acupuncture treatment for irritable bowel syndrome. Method Sixty patients diagnosed with irritable bowel syndrome were enrolled from Jan. 2008 to Dec. 2010. They received eye acupuncture treatment. Fasting venous blood 8 mL was taken before and after treatment. The blood was centrifuged and refrigerated for pre-/post-treatment quantitative measurement of immunological indicators. Result The 5-HT content was significantly lower after eye acupuncture treatment E （267.28±105.74）mol/L] than before E （313.07 ± 110.63）mol/L]; there was a statistically significant pre-/post-treatment difference （P〈0.05）. Conclusion Eye acupuncture produces a therapeutic effect on irritable bowel syndrome of diarrhea type through decreasing the 5-HT content, which reveals part of the biological mechanisms of its treatment for irritable bowel syndrome.