双源双能CT在尿路结石成分分析中的应用

Dual source dual energy CT in the analysis of urinary calculi composition

目的:探讨双源CT双能量技术应用于尿路结石成分分析中的临床价值。方法:226例尿路结石患者行双源CT双能量扫描,对其结石成分进行分析,将结果与用红外光谱法分析结石成分的结果作对比,计算双源CT在体分析草酸钙结石、磷酸盐结石、胱氨酸结石及尿酸结石的灵敏度与特异度。结果:双源CT能够准确的区分尿酸结石和非尿酸结石(灵敏度和特异度均为100%),较准确的区分草酸钙结石(灵敏度为89.03%、特异度为85.62%),磷酸盐结石(灵敏度为67.28%、特异度为90.71%)及胱氨酸结石(灵敏度为73.56%、特异度为93.43%)。结论:双源CT双能量技术能在治疗前对尿路结石的成分进行初步分析,对了解结石成因,预防结石形成及指导治疗具有重要的意义。

Objective：To assess the clinical value of dual source dual energy CT in the analysis of urinary calculi composition.Methods：Dual-source CT with dual-energy scanning technique was performed in 226 patients with urinary calculi.The composition of urinary stones was compared with the results of the urinary stones composition analyzed by Fourier transform infrared spectroscopy（FTIR）.The sensitivity and specificity of dual energy CT in evaluating the composition of calcium oxalate stone、 phosphate stone、 cystine stone and uric acid stone in vivo were calculated.Results：Dual-source CT could accurately distinguish uric acid stones and non-uric acid stones with the sensitivity and specificity as 100% respectively.The sensitivity of differentiating calcium oxalate stone,cystine stone and phosphate stone was 89.3%,67.28% and 73.56% respectively,and the specificity of the above mentioned calculi was 85.62%,90.71% and 93.43% respectively.Conclusion：Analysis of urinary calculi composition before treatment could be obtained by dual-source CT with dual-energy technique,which had significant importance to understand the causes of stone,to prevent stone formation and provide treatment guidance.