Wilson-Mikity综合征的X线及CT诊断

Pulmonary CT and radiography in the diagnosis of Wilson-Mikity syndrome

目的:探讨X线及CT在Wilson-Mikity综合征诊断中的应用价值。方法:回顾性分析16例临床确诊的Wilson-Mikity综合征患儿的临床及影像学资料。16例患儿在疾病的早、中、晚期均进行了胸部X线检查,7例行CT检查。结果:7例出生后1周内胸片未见异常;16例出生后2～3周内胸片显示:13例双肺弥漫性片状和索条状间质浸润,14例其间有小的囊状透亮区出现;双肺基底部多个小囊状病灶,其中5例融合扩大并扩展到上肺野以下肺野明显,肺透亮度增加。7例胸部CT表现为间质性肺炎、小囊状透亮影及小叶性肺气肿。结论:X线及CT能反映Wilson-Mikity综合征的特征性影像表现,对诊断有重要价值,在明确病灶范围及形态上,CT较X线更有优势。

Objective：To study the value of pulmonary radiography and CT in the diagnosis of Wilson-Mikity syndrome（WMS）.Methods：The clinical and imaging materials of 16 cases with clinically diagnosed Wilson-Mikity syndrome were analyzed retrospectively.Pulmonary radiography was performed in early,mid and advanced periods of all 16 cases and 7 cases had CT plain scan.Results：The major findings of pulmonary radiography and CT of Wilson-Mikity syndrome were as follows：no abnormal changes were observed in 7 cases within 1 week after parturition.Of the 16 cases checked 2~3 weeks after parturition,there were bilateral diffuse patchy and streaky interstitial infiltrations throughout the lung（13 cases）,small cystic translucency within the above-mentioned areas（14 cases） was observed.In 5 cases,there were multiple small sacciform translucencies within bilateral basal parts of lungs,part of which coalesced and expanded to the upper lung fields with over-distension of lower lung fields presented as pulmonary hyper-translucency.Conclusion：Characteristic imaging appearances of Wilison-Mikity syndrome could be displayed on CT and pulmonary radiography,which provide significant value for the diagnosis.CT is superior to pulmonary radiography in showing the extent and morphology of the disease.