不同方法注射利多卡因对预防儿童丙泊酚注射痛的效果比较

Different methods of injection of lidocaine in the prevention of children with propofol injection pain

目的:比较预注和混用利多卡因对于儿童丙泊酚静脉注射痛的预防作用。方法:120例儿外科患儿分为A组(先静脉注射0.5 mg/kg利多卡因30 s后使用注射丙泊酚全麻诱导)和B组(丙泊酚和1%利多卡因按20∶1混合液全麻诱导),每组均为60例,观察患儿从开始注射丙泊酚到意识消失过程中出现的注药手臂运动情况和面部表情的反应,评估疼痛的发生率和强度。结果:A组注射痛的发生率为68.3%,其中中重度痛(中度痛+重度痛)发生率为38.3%。B组注射痛的发生率为36.7%,其中中重度痛发生率为18.3%。两组相比,B组注射痛及中重度痛的发生率均明显降低(均P<0.01)。结论:丙泊酚和1%利多卡因按20∶1混合液较预注射0.5 mg/kg利多卡因30 s后注射丙泊酚更能有效缓解患儿注射痛。

Objective To compare pre-injection and mix-lidocaine to reduce propofol injection pain for children.Methods Choosing 120 veinous general anesthesia children patients,they were randomly allocated into two groups： Group A patients were injected propofol after lidocaine（0.5 mg/kg）injected 30 s,Group B patients were injected lidocaine and propofol mixed liquid.Using a four-point scale evaluate the effect on the prevention of pain on the propofol injection.Result 68.3% patients of pain in group A as compared with 36.7% in group B（P 0.05）.Conclusion Lidocaine and propofol mixed liquid can effectively alleviate the children of propofol injection pain.