2Ma S,Ma C C.Recent development in pleiotropic effects of statins on cardio-vascular disease through regulation of transforming growth factor-beta superf-amily[J].Cytokine Growth Factor Rev,2011,22(3):167-175.
3Mitsios J V,Papathanasiou A I,Goudevenos J A,et al.The antiplatelet and antithrombotic actions of statins[J].Curr Pharm Des,2010,16(34):3808-3814.
4Salat D,Ribosa R,Garcia-Bonilla L,et al.Statin use before and after acuteischemic stroke onset improves neurol-ogical outcome[J].Expert Rev Cardi-ovasc Ther,2009,7(10):1219-1230.
5Montaner J,Chacon P,Krupinski J,et al.Simvastatin in the acute phase of ischemic stroke:a safety and efficacy pilot trial[J].Eur J Neurol,2008,15(1):82-90.
6Lakhan S E,Bagchi S,Hofer M.Statins and clinical outcome of acute ischemic stroke:a systematic review[J].Int Arch Med,2010,3:22.
7Wang L,Zhang X,Liu L,et al.Atorvastatin protects rat brains against permanent focal ischemia and downregulates HMGB1,HMGB1recept-ors(RAGE and TLR4),NF-kappaB expre-ssion[J].Neurosci Lett,2010,471(3):152-156.Szczepanska-Szerej A,Kurzepa J,
8Wojczal J,et al.Simvastatin displays an antioxidative effect by inhibiting an increase in the serum8-isoprostane level in patients with acute ischemic stroke:brief report[J].Clin Neuroph-armacol,2011,34(5):191-194.
9Elkind M S,Sacco R L,MacArthur R B,et al.The Neuroprotection with Statin Therapy for Acute Recovery Trial(NeuSTART):an adaptive design phase I dose-escalation study of high-dose lovastatin in acute ischemic stroke[J].Int J Stroke,2008,3(3):210-218.
10Armitage J,Bowman L,Wallendszus K,et al.Intensive lowering of LDL cholesterol with80mg versus20mg simvastatin daily in12,064survivors of myocardial infarction:a double-blind randomised trial[J].Lancet,2010,376(9753):1658-1669.
二级参考文献13
1Gidday J M, Gasche Y G, Copin J C, et al. Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is pro-inflammatory after transient focal cerebral ischemia [J]. Am J Physiol Heart Cire Physiol, 2005,289: 558- 568.
2Wang X, Jung J, Asahi M, et al. Effects of metalloproteinase-9 gene knock-out on morphological and motor outcomes after traumatic brain injury [J]. J Neurosci, 2004,24 (18) :7037- 7042.
3Tenger C, Sundborger A, Jawien J, et al. IL-18 accelerates atherosclerosis accompanied by elevation of IFN-r and CXCL-16 expression independently of T cells [ J ]. Arterioscler Thromb Vasc Bioy, 2005,25(4) :791-796.
1Flint AC, Conell C, Rao VA, et al. Effect of Statin Use During Hospitali- zation for Intracerebral Hemorrhage on Mortality and Discharge Disposi- tion[ J]. JAMA Neurol,2014,71 ( 11 ) : 1364 - 1371.
3Cui JJ, Wang D, Gao F, et al. Effects of atorvastatin on pathological changes in brain tissue and plasma MMP-9 in rats with intracerebral hemorrhage [ J ]. Cell Biochem Biophys ,2012,62 ( 1 ) :87 - 90.
4Pan YS, Jing J, Wang YL, et al. Use of statin during hospitalization im- proves the outcome after intracerebral hemorrhage [ J ]. C NS Neurosci T- her,2014,20:548 - 555.
