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小剂量克拉霉素治疗慢性鼻-鼻窦炎疗效观察 被引量:3

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摘要 目的分析小剂量克拉霉素治疗慢性鼻-鼻窦炎的疗效。方法25例慢性鼻-鼻窦炎(不伴鼻息肉)患者采用克拉霉素片剂250mg,1次/d,口服,疗程3个月。术前术后按照视觉模拟量表(VAS)评估患者的主观症状及鼻窦CT扫描结果,量化评估采用Lund-Mackay评分法。结果25例慢性鼻窦炎患者治疗前VAS评分为(5.20±2.50)分,克拉霉素治疗3个月后VAS评分为(3.28±1.86)分,差异有统计学意义(P=0.03)。治疗前鼻窦CT发现19例为双侧鼻窦炎症,按侧进行Lund—Mackay鼻窦CT评分,共有44侧。治疗前后轻微炎症组和轻度炎症组与中度炎症组和重度炎症组的例数变化,差异有统计学意义(P〈0.05)。治疗前Lund.Mackey鼻窦CT评分为(8.16±4.26)分,治疗后为(5.44±2.74)分,差异有统计学意义(P〈0.01)。结论小剂量克拉霉素治疗慢性鼻一鼻窦炎(不伴鼻息肉)有一定的效果。
作者 樊生凯
出处 《中国实用医刊》 2012年第9期110-111,共2页 Chinese Journal of Practical Medicine
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