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血小板衍生生长因子-B与冠心病研究进展 被引量:5

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摘要 血小板衍生生长因子(platelet—derivedgrowthfactor,PDGF)是24ku的阳离子糖蛋白,主要存在于血小板a颗粒中,也存在于受损的内皮细胞、移行于内皮下的巨噬细胞、平滑肌细胞(smoothmusclecell,SMC)、成纤维细胞、系膜细胞等细胞中。这些细胞以白分泌、旁分泌”,的连锁放大反应形式大量释放PDGF,介导多种组织中内皮与间质的相互作用。
作者 路雅茹 秦勤
出处 《天津医药》 CAS 北大核心 2012年第5期525-527,共3页 Tianjin Medical Journal
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参考文献27

  • 1Korpisalo P, Karvinen H, Rissanen T, et al. Vascular endothelial growth factor-A and platelet-derived growth factor-B combination gene therapy prolongs angiogenic effects via recruitment of intersti- tial mononuclear cells and paracrine effects rather than improved pericyte coverage of angiogenic vessels[J]. Circ Res, 2008, 103(10): 1092-1099.
  • 2Yamamoto S, Fukumoto E, Yoshizaki K, et al. Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fi- broblast growth factor expression[J]. J Biol Chem, 2008, 283(34): 23139-23149.
  • 3Sabuda-Widemann D, Grabensee B, Schwandt C, et al. Mycopheno- lic acid inhibits the autocrine PDGF-B synthesis and PDGF-BB-induced mRNA expression of Egr-I in rat mesangial cells[J]. Nephrol Dial Transplant, 2009, 24(1): 52-61.
  • 4Hye-Ryong Shim A, Liu H, Focia PJ, et al. Structures of a plate- let-derived growth factor/propeptide complex and a platelet-de- rived growth factor/receptor complex[J]. PNAS, 2010, 107(25): 11307-11312.
  • 5Andrae J, Gallini R, Betshohz C, et al. Role of platelet-derived growth factors in physiology and medicine[J]. Genes Dev, 2008, 22: 1276-1312.
  • 6Cagnin S, Biseuola M, Patuzzo C, et al. Reconstruction and function- al analysis of altered molecular pathways in human atherosclerotic arteries[J]. BMC Genomics, 2009, 10:13.
  • 7Cha BY, Shi WL, Yonezawa T, et al. An Inhibitory Effect of chrys- oeriol on platelet-derived growth factor (PDGF)-induced prolifera- tion and PDGF receptor signaling in human aortic smooth muscle cells[J]. J Pharm'acol Sci, 2009,110 (1): 105-110.
  • 8Jiang H, Chen J, Wang L, et al. Down-regulation of CREB-binding protein expression inhibits thrombin-induced proliferation of endo- thelial ceils: possible relevance to PDGF-B[J]. Cell Biol Int, 2010, 34(12):1155-1161.
  • 9Qi YX, Jiang J, Jiang XH, et al. PDGF-BB and TGF-{beta}l on cross-talk between endothelial and smooth muscle cells in vascular remodeling induced by low shearstress[J]. Proc Natl Acad Sci USA, 2011,108(5):1908-1913.
  • 10Billett MA, Adbeish IS, Alrokayan SA, et al. Increased expression of genes for platelet-derived growth factor in circulating mononuclear cells of hypercholesterolemic patients[J]. Arterioscler Thromb, 1996, 16(3):399-406.

二级参考文献5

  • 1Cecena FA.Stenting stent: alternative strategy for treating instent restenosis.Cathet Cardiovasc Diagn, 1996, 39 (4): 377-382.
  • 2Hoffmann R, et al, Patterns and mechanisms of in - stent restenosis: serial intravascular ultrasound study [J] .Circulation, 1996, 94:1247 -1254.
  • 3Ihling C. Pathomorphology of coronary atherosclerosis [ J ] .Herz, 1998,23: 69-77.
  • 4M orishita R, Euison KE, et al. Evdence fordirect local effect of angiotension in yascaular hypertrophy invivogene transfer of angioteusin converting enzyme [J].J clininvest, 1994, 94: 978-984.
  • 5Cereck B, et al.Induction of insulinlike growth factor Ⅰ messenger RNA in rat aorta after ballon denudation. Circ Res, 2000, 66:1755 - 1761.

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