金黄如意膏联合地塞米松治疗儿童急性附睾炎的研究

Jinhuangruyi ointment combined with dexamethasone in the treatment of children acute epididymitis

目的探讨金黄如意膏联合地塞米松治疗儿童急性附睾炎的临床疗效。方法选取2003年10月至2011年7月间在本院就诊的急性附睾炎患儿27例，按数字表法随机分为抗生素组13例（给予抗生素、金黄如意膏加地塞米松治疗）和无抗生素组14例（给予金黄如意膏加地塞米松治疗），观察其疗效。结果抗生素组和无抗生素组患儿经治疗后，附睾无触痛率分别为84．62％和85．71％，两组差异无统计学意义（Х^2=0．01，P〉0．05）；肿块完全消退率差异也无统计学意义（84．62％：71．43％，Х^2=0．68，P〉0．05）。无抗生素组治愈率（71．43％）略低于抗生素组（84．62％），但差异无统计学意义（z0=0．68，P〉0．05）。治疗后，抗生素组和无抗生素组WBC均有明显下降，与治疗前比较差异均有统计学意义（t=7．53、7．28，P〈0．01）；治疗前后，两组组间WBC差异均无统计学意义（t=0．33、0．51，P〉0．05）。结论金黄如意膏联合地塞米松治疗儿童急性附睾炎疗效确切，可适当避免抗生素的不合理使用，值得在临床推广使用。

Objective To investigate the effect of jinhuangruyi ointment combined with dexamethasone in the treatment of acute epididymitis in children. Methods Twenty-seven children of acute epididymitis from October 2003 to July 2011 in our hospital were devided randomly into antibiotic group （antibiotic, jinhuangruyi ointment and dexametha- sone） and non-antibiotic group （firdmangruyi ointment and dexamethasone）. All the patients were surveyed for the effects. Results The non-tenderness rates in antibiotic and non-antibiotic group after treatment were 84.62% and 85.71% respectively. No significant differences were found in non-tenderness rates （Х^2 = 0.01, P 〉 0.05） and in swelling subsided rate between two groups （84.62% ： 71.43 %, Х^2 = 0.68, P 〉 0.05）. The curative rate in non-antibiotic group （71.43 % ） was slightly lower than that in antibiotic group（84.62 % ）, but no statistical significant difference was found between them（ Z2 = 0.68, P 〉 0.05）. The white blood cell count were significantly reduced in antibiotic group and non-antibiotic group after treatment（ t = 7.53, 7.28, P 〈 0.01 ）, but there was no significant difference in white blood cell count change between two groups before and after treatment（ t = 0.33, 0.51, P 〉 0.05）. Conclusions That jirdumngruyi ointment combined with dexamethasone is effective in acute epididymitis treatment and can avoid irrational antibiotics consumption. It is worthy for clinical application.