经尿道超脉冲等离子体双极电切术联合膀胱灌注化疗治疗腺性膀胱炎44例

Tansurethral bipolar plasmakinetic superpulse resection combined with intravesical chemotherapy in treatment of cystitis glandularis:Report of 44 cases

目的探讨经尿道超脉冲等离子体双极电切术联合膀胱灌注化疗治疗腺性膀胱炎的临床疗效。方法回顾分析我院2006年1月到2010年12月接受尿道超脉冲等离子体双极电切术联合膀胱灌注化疗治疗的44例腺性膀胱炎患者临床资料。男性15例,女性29例,年龄24～72岁,平均48.5岁。术后即刻膀胱灌注化疗,后定期膀胱灌注化疗。结果 44例手术顺利,手术时间10～125 min,平均42.5 min,术中出血量少。随访3～62个月,平均14.8个月,2例尿道外口狭窄。12例复发,复发病例均再次手术处理,9例治愈,3例肾积水。结论经尿道超脉冲等离子体双极电切术联合膀胱灌注化疗治疗腺性膀胱炎,具有安全、并发症少、疗效确切等优点,但远期疗效尚需进一步研究。

Objective To evaluate the clinical efficacy and safety of the tansurethral bipolar plasmakinetic superpulse resection combined with intravesical chemotherapy in treatment of cystitis glandularis. Methods The data of 44 patients with cystitis glandularis treated with transurethral bipolar plasmakinetic superpulse resection combined with intravesical chemotherapy from January 2006 to December 2010 were reviewed and evaluated. There were 25 males and 19 females between 24 and 72 years old （mean, 48.5 years）. Immediate bladder instillation and regular intravesical chemotherapy after surgery were underwent in all patients. Results The duration of the procedure was 10 to 125 min （mean, 42.1 min） with little bleeding. 44 patients were treated successfully and followed up from 3 to 62 months （mean, 14.8 months）. Two cases were found urethral stenosis, 12 cases recurrence after the operation and 9 of them were cured by the second operation and 3 of them still with hydronephrosis. Conclusions Tansurethral bipolar plasmakinetic superpulse resection combined with intravesical chemotherapy in treatment of cystitis glandularis has advantages of high safety, fewer complications and satisfactory efficacy, but long follow-up is recommended.