女性平板运动试验前后QTc离散度变化的意义

Significance of the change of QTc dispersion before and after treadmill exercise test in female

目的 探讨女性运动试验前后 QTc离散度 ( QTcd)的变化 (△ QTcd)意义。方法 随机选取经冠状动脉造影证实的冠心病和非冠心病各 30例 ,对比观察它们在平板运动试验前后的 QTcd和△ QTcd。结果 ( 1)冠心病组运动后 QTcd较运动前显著延长 ( P<0 .0 0 1) ,非冠心病组运动后 QTcd较运动前无明显延长 ( P>0 .0 5 ) ,冠心病组的△ QTcd( 2 3± 12 ms)较非冠心病组的△ QTcd( 2± 10 m s)显著增大( P<0 .0 0 1)。 ( 2 )以△ QTcd>10 ms为运动试验阳性标准 ,诊断冠心病的敏感性、特异性和阳性预测值明显优于 ST段标准 ( 93%对 73% ,90 %对 6 7%和 90 %对 6 9% ,P均 <0 .0 5 )。结论 △ QTcd>10

Objective To evaluate significance of the change of QTc dispersion(QTcd)before and after treadmill exercise test in female.This change is called △QTcd.Methods Sixty cases were studed,which included 30 cases of coronary artery disease(CAD) and 30 cases of non-CAD confirmed by coronary angiography.Their QTcd were measured before and 2 min after treadmill exercise tests,and the △QTcd were then evaluated.Results (1)QTcd of CAD group were proved to be much longer after tests than before(P<0001).QTcd of non-CAD group showed non remarkble increase after tests(P>0.05).△QTcd(23±12ms) in the former were significantly greater than that (2±10ms) in the latter(P<0.001).(2)For the diagnosis of CAD,there were higher sensitivity,specificity and positive predictability when △QTcd>10ms served as an positive indicator than ST segment depression(93% vs.73%,90%vs. 67%,90% vs. 69%,P all<0.05)Conclusion △QTcd>10ms could serve as an excellent indicator to judge positive treadmill exercise test in female.