粒细胞集落刺激因子对胎膜早破合并羊膜腔感染的预测意义

目的:评价粒细胞集落刺激因子(G-CSF)在预测无症状胎膜早破合并羊膜腔感染中的作用。方法:检测50例无症状胎膜早破患者(研究组)血清粒细胞集落刺激因子含量,并与同期50例正常妊娠(对照组)比较。结果:研究组并发无症状绒毛膜羊膜炎高于对照组(60%VS4%,P<0.05),其并发无症状绒毛膜羊膜炎者血清粒细胞集落刺激因子含量高于未并发绒毛膜羊膜炎者,差异有显著性(P<0.05)。结论:胎膜早破并发无症状绒毛膜羊膜炎时粒细胞集落刺激因子含量升高,粒细胞集落刺激因子可作为胎膜早破合并羊膜腔感染的预测因子。

Objective： Evaluation of granulocyte colony - stimulating factor（ G - CSF） in predicting intra - amniotic infection in asymptomatic premature rupture of membranes combined role. Methods：Detected 50 cases of asymptomatic patients with premature rupture of membranes （ study group ） serum granulocyte colony - stimulating factor levels, and compared with 50 normal pregnancies （ control group） to compare. Results ： Group of concurrent symptoms of chorioamnionitis was higher （60% VS4%, P 〈 0. 05）, the concurrent symptoms of chorioamnionitis in serum granulocyte colony - stimulating factor levels than those who are not complicated by chorioamnionitis, there was a significant difference （ P 〈 0. 05 ）. Conclusion： Asymptomatic rupture of membranes complicated by chorioamnionitis when granulocyte colony - stimulating factor levels increased, granuloeyte colony - stimulating factor as premature rupture of mere-branes combined predictor of intra - amniot- ic infection.