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川崎病患儿血浆D-二聚体变化及其意义 被引量:1

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摘要 目的:探讨D-二聚体在川崎病(KD)病程中的动态变化及与KD合并冠状动脉病变之间的关系。方法:监测比较KD组和对照组、KD患儿急性期和恢复期血浆的D-二聚体、血沉(ESR)和C-反应蛋白(CRP)的指标变化,并比较冠状动脉病变(CAD)与无冠状动脉病变组(NCAD)急性期与恢复期D-二聚体水平变化。结果:KD组患儿急性期的D-二聚体、ESR、CRP,与对照组比较,差异均有统计学意义(P<0.05);与KD组恢复期比较,差异均有统计学意义(P<0.05)。CAD组的KD急性期、恢复期患儿D-二聚体水平高于NCAD组,差异均有统计学意义(t分别=2.08、2.09,P均<0.05)。结论:D-二聚体可作为KD诊断及预后的重要指标之一。
作者 杨永朝
出处 《中国社区医师(医学专业)》 2012年第10期279-280,共2页
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