脑肠互动与针刺治疗功能性胃肠病的相关性

Correlation between the brain-gut interaction and acupuncture treatment of functional gastrointestinal disorders

功能性胃肠病是临床上常见的消化系统疾病,也是针刺治疗的优势病种.近年来的研究表明,脑肠轴功能失调是功能性胃肠病发病的重要原因,而针刺对脑肠轴的调节作用是其治疗功能性胃肠病的主要着眼点.随着脑功能成像技术的发展和脑肠肽研究的进展,功能性胃肠病与中枢神经系统及脑肠肽代谢相关性的研究日益增多.针灸作为传统中医疗法的一部分,治疗功能性胃肠病疗效显著,被广泛运用于临床.大量研究显示,针刺既能调节中枢神经系统,也能调控脑肠肽代谢.本文拟从中枢神经系统、脑肠肽代谢两方面,探讨脑肠互动与针刺治疗功能性胃肠病的相关性.

Acupuncture has been proven to be effective in treating functional gastrointestinal disorders（FGIDs）,which are common digestive diseases.Recent studies have proven that dysfunction of the ＂Brain-Gut-Axis＂（BGA） might be an important pathogenetic factor for FGIDs.The curative effect of acupuncture on FGIDs could mainly be attributed to its modulation effect on the BGA.Increasing attention has been paid to the study of the interaction between the central nervous system and brain-gut peptide in patients with FGIDs due to the development of functional imaging and the progress in research of the brain-gut peptide.Acupuncture has been extensively used in treating FGIDs clinically.Substantial studies have shown that acupuncture could modulate the central nervous system and the brain-gut peptide.In this article we are going to summarize the correlation between the brain-gut interaction and the curative effect of acupuncture in terms of central nervous system and the metabolism of brain-gut peptide.