胰岛素泵在老年糖尿病酮症酸中毒中的应用

Application of insulin pump in elderly patients with diabetic ketoacidosis

目的探讨胰岛素泵在老年糖尿病酮症酸中毒(DKA)中的应用价值。方法 60例老年DKA患者分为观察组和对照组,每组30例;观察组患者给予胰岛素泵持续皮下注射给药,对照组患者给予常规小剂量胰岛素静脉滴注。观察比较2组患者的血糖达标时间,血、尿酮体恢复时间及低血糖发生情况。结果观察组患者血糖达标时间、血酮体恢复时间、尿酮体恢复时间均显著短于对照组(P<0.01),观察组患者低血糖发生次数显著少于对照组(P<0.01)。结论胰岛素泵持续皮下给药治疗老年DKA,可有效地、较快地控制高血糖,且低血糖发生率低。

Objective To investigate the application value of insulin pump in elderly patients with diabetic ketoacidosis（DKA）. Methods Sixty elderly patients with DKA were divided into observation group and control group,thirty patients in each group.The patients in observation group were treated with continuous subcutaneous administration by insulin pumps;the patients in control group were treated with conventional low-dose insulin by intravenous drip.The blood glucose coincidnece time,blood ketone body coincidnece time,urine ketone body coincidnece time and glycopenia were observed and compared between two groups. Results The blood glucose coincidnece time,blood ketone body coincidnece time and urine ketone body coincidnece time in observation group were significantly shorter than those in control group（P0.01）.The glycopenia frequency in observation group was significantly less than that in control group（P0.01）. Conclusion The treatment of continuous subcutaneous administration by insulin pump for elderly patients with DKA can effectively and quickly control high blood sugar,and the glycopenia incidence is low.