无线血压传感器压力遥测腹主动脉瘤覆膜支架腔内修复后内漏的可行性

An invasive telemetric pressure sensor for detecting endoleaks after endovascular abdominal aortic aneurysm stent repair

背景:腹主动脉瘤覆膜支架腔内修复后内漏的检查方法主要有螺旋CT、动脉造影、核磁共振、多普勒超声等,但都是通过影像间接判断的,无法实现对内漏的直接有效检查,存在漏诊、操作复杂、检查成本高、对患者有一定创伤等缺点。目的:采用植入式无线血压传感器长期监测腹主动脉瘤修复术后瘤腔内血压,用于诊断是否发生内漏。方法:用于腹主动脉瘤修复后内漏诊断的压力无线检测系统由植入式无线血压传感器、能量发射线圈、数据读取器和数据处理平台组成。植入式无线血压传感器直接检测瘤腔内血压。无线血压传感器由无线能量接收模块、电源管理模块、传感器模块、信号调理模块、微控制器和射频通讯模块组成。结果与结论:目前已经完成了样机的研制,并进行了体外模拟血压测试实验。通过模拟实验,初步验证了无线血压传感器进行压力遥测的可行性及有效性。

BACKGROUND：To date,the method for detecting endoleaks after endovascular abdominal aortic aneurysm stent repair include spiral computed tomography（CT） scan,artery angiography,magnetic resonance imaging,or duplex ultrasound scanning.But all the results are judged by the image indirectly and cannot examine the endoleaks directly and efficiently.The shortages exist,such as miss diagnosis,complicate to operate,high cost and another disadvantages to patients.OBJECTIVE：To measure the pressure in cavity by using the implantable wireless invasive telemetric pressure sensor in order to diagnose the occurrence of endoleaks after endovascular abdominal aortic aneurysm stent repair METHODS：The implantable wireless pressure detection system consisted of an invasive telemetric pressure sensor,power transmitting coil,data recorder and data processing station.The implantable wireless invasive telemetric pressure sensor could detect the blood pressure in tumor cavity.The implantable wireless invasive telemetric pressure sensor was composed of the wireless energy receiving module,the power management module,the sensor module,the signal conditioning module,the microcontroller and the radio frequency communication module.RESULTS AND CONCLUSION：The prototype has been made and the in vitro blood test experiment has been carried out.Through the simulation test,the feasibility and effectiveness of the pressure telemetry for the wireless pressure sensors has been verified preliminary.