反复呼吸道感染患儿红细胞免疫功能变化

Variation of Erythrocyte Immune Function in the Children with Recurrent respiration tract infection

目的研究反复呼吸道感染患儿红细胞免疫功能的改变,探讨红细胞免疫系统与小儿反复呼吸道感染的关系。方法应用红细胞酵母花环结合率方法分别测定2组红细胞免疫黏附功能。结果 (1)反复呼吸道感染患儿存在红细胞C3b受体活性低下(P<0.05),其表面免疫复合物明显增多(P<0.05);(2)反复呼吸道感染患儿发病次数与红细胞免疫功能呈负相关。结论反复呼吸道感染患儿存在红细胞免疫功能低下,红细胞免疫功能降低与该病的发生有一定的相关性。

Objective To investigate the variation of erythrocyte immune function in the children with recurrent respiration tract infection and explore the relationship between the erythrocyte immune function and recurrent respiration tract infection.Method s Erythrocyte yeast-SPA mixed rosette were applied to measure erythrocyte immune function.Results （1）RBC- CR1 decreased compared with healthy control subjects（P〈0.05）;While RBC-ICR increased compared with healthy control subjects（P〈0.05）.（2）Morbidity frequency of RRTI has negative correlation with erythrocyte immune function.Conclusion There is a decrease in erythrocyte immune function in the children with recurrent respiration tract infection.And there is some relationship between the decrease of erythrocyte immune function and recurrent respiration tract infection.