相转移催化法合成对甲氧基苯乙醇酸的研究

Study on Synthesis of 4-Methoxy-phenylhydroxy-acetic acid by PTC

以对甲氧基苯甲醛、三氯甲烷为原料,相转移催化羰基加成法合成了对甲氧基苯乙醇酸。分析探讨了其相转移催化机理及合成工艺参数。

Based on the principle of phase transfer catalysis, 4-methoxy-phenylhydroxy-acetic acid was synthesized by the carbonyl addition reaction of 4-methoxybenzaldehyde. The mechanism of phase transfer catalysis was analyzed and the process parameters were evaluated. The yield of the product was 80%.