微波对烯丙基芳醚的Claisen重排反应影响研究

Study on the Microwave Effect in the Claisen Rearrangement of the Allyl Phenyl Ethers

5种烯丙基芳醚衍生物在无溶剂、无催化剂的条件下进行Claisen重排反应,采用了微波加热和常规加热方式,比较了同等温度下微波加热和常规加热反应速率的差异.结果表明微波加热可以显著提高烯丙基苯醚Claisen重排反应的速率.反应温度为190℃时,微波加热下反应速率可提高5～10倍.微波加热是一种无催化剂、高产率的Claisen重排反应的方法.

olvent-free and catalyst-free Clasien rearrangement of five kinds of allyl phenyl ethers were investigated under microwave heating and conventional heating respectively.The effects on the reaction rates by microwave heating and conventional heating were compared.The results demonstrate that microwave heating could greatly accelerate the reaction rate of the Claisen rearrangement.The reaction rates under microwave heating are 5～10 times higher than those acted by conventional heating at 190 ℃.The microwave heating is an efficient method of catalyst-free,high yield of Claisen rearrangement.