直接免疫荧光检查对大疱性皮肤病及疱疹样皮炎的临床意义

CLINICAL SIGNIFICANCE OF DIRECT IMMUNOFLUORESENCE IN BULLOUS DERMATOSIS AND DERMATITIS HERPETIFORMIS

作者用直接免疫荧光技术检测了7例天疱疮,1例类天疱疮和2例疱疹样皮炎病人的皮损或“正常”皮肤,检查结果:总阳性率为80%、荧光强度可作为判断疾病活动和治疗的参考指标,直接免疫荧光技术对早期诊断大疱性皮肤病及疱疹样皮炎有一定的临床意义。

The authors determinated the lesion or 'normal' skin of patients, 7cases with pemphigus, 1 case with pemphigoid, and 2 with dermatitisherpetiformis using direct immunofluoresence (DIF).Results:the positiverate was 80%.The fluorescence intencity might be as a reference index to judge the disease activity and treatment.DIF was helpful for early diagnosis ofbullous dermatosis and dermatitis herpetiformis.