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胎膜早破孕妇血清中IL-6、高敏CRP的变化和意义 被引量:3

Changes and significance of IL-6 and high-sensitivity CRP in serum ofpregnant women with premature rupture of membranes
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摘要 目的 研究胎膜早破孕妇血清中白介素-6(IL-6)、高敏C反应蛋白(hs-CRP)的变化和意义,为寻找胎膜早破的病因提供新思路,为临床治疗提供理论依据.方法 利用酶联免疫吸附实验(ELISA)检测孕妇血清中IL-6水平,速率散射比浊法测定血清hs-CRP水平,比较不同组别间IL-6和hs-CRP的水平,探讨IL-6、hs-CRP的相关性.结果 胎膜早破孕妇血清IL-6(13.06±0.45 pg/mL vs 6.32±1.06pg/mL,t=5.46,P〈0.01)、hs-CRP(3.76±0.75 mg/L vs 0.86±0.25 mg/L,t=4.52,P〈0.05)表达均明显高于对照组;IL-6和hs-CRP之间呈正相关,r=0.493,P〈0.05.结论 IL-6和hs-CRP水平增高对预测胎膜早破有重要意义.
出处 《中国妇幼健康研究》 2012年第2期213-214,共2页 Chinese Journal of Woman and Child Health Research
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