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8例妊娠期急性脂肪肝治疗分析

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摘要 目的探讨妊娠期急性脂肪肝的诊治。方法对本院妇产科2001年1月至2011年1月收治的8例妊娠期急性脂肪肝患者的临床资料进行回顾性分析。结果8例均发生于妊娠晚期,初产妇6例,经产妇2例;单胎妊娠6例,双胎2例;男胎8例,女胎2例。均有明显的临床症状、体征和实检室检查特征;其中7例合并妊娠期高血压疾病,6例出现肝、肾、心和肺等多器官功能衰竭(MOF);B超诊断妊娠期急性脂肪肝8例,未作cT和肝穿;8例经过积极治疗后均剖宫产终止妊娠,其中4例术后予以血滤治疗(CRTT),抢救成功6例(75.0%),产妇死亡率25%(2/8)。产后出血率50%(4/8);无一例围产儿死亡,新生儿窒息率50%(4/8)。结论妊娠期急性脂肪肝死亡率高,妊娠期急性脂肪肝早期发现,给予血滤治疗、补充凝血因子及行剖宫产术终止妊娠,能改善预后。血滤治疗(CRRT)是提高产妇预后的必要措施。
出处 《中国医师杂志》 CAS 2012年第3期375-376,共2页 Journal of Chinese Physician
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