期刊文献+

珍稀药用植物明党参呋喃香豆素成分累积分布研究 被引量:6

Accumulation and Distribution of Furanocoumarins in Rare Medicinal Plants Changium smyrnioides Wolff
下载PDF
导出
摘要 采用HPLC法测定明党参不同器官、不同生长期中珊瑚菜内酯、5-羟基-8-甲氧基补骨脂素的含量。结果表明,明党参根、茎叶、花葶及果实均含有2种呋喃香豆素,2种呋喃香豆素总量,根中以6月为最高,为163.8467μg/g;茎叶以1月为最高,为606.1023μg/g;花葶以6月上旬(生长发育接近成熟时)为最高,为117.1185μg/g;果实以成熟期为最高,达1070.6326μg/g。提示明党参药用器官(根)和非药用器官(茎叶、花葶、果实)为天然呋喃香豆素优质药用植物资源,具有广泛开发利用的前景。 HPLC method was used to determine the contents of phellopterin and 5-hydroxyl-8-methoxy-psoralen in Changium smyrnioides Wolff collected from different organs and different periods of growth.The results showed that roots,stems,leaves,scapes and fruits of C.smyrnioides contain two furanocoumarins.In the roots,the total contents of two furanocoumarins were highest in June reaching 163.8467 μg/g.In the stems and leaves,the contents were highest in January reaching 606.1023 μg/g.In the scapes,the contents were highest in early June when the scapes were grown close to maturity reaching 117.1185 μg/g.Furanocoumarins in fruit of C.smyrnioides(to maturity) was the highest,and reached 1070.6326 μg/g.C.smyrnioides is a high quality medicinal plant resource for natural furanocoumarins,including the medicinal and the non-medicinal parts of the plant.It has great potential that is worthy for further exploration.
出处 《天然产物研究与开发》 CAS CSCD 北大核心 2012年第4期510-513,共4页 Natural Product Research and Development
基金 教育部高等学校博士学科点专项科研基金资助课题(200803150009) 江苏高校优势学科建设工程资助项目 江苏省自然科学基金项目(BK2003107) 国家药典研究项目(YZ-124)
关键词 明党参 呋喃香豆素 珊瑚菜内酯 5-羟基-8-甲氧基补骨脂素 累积分布 Changium smyrnioides Wolff furanocoumarins phellopterin 5-hydroxyl-8-methoxy psoralen cumulative distribution
  • 相关文献

参考文献11

  • 1Fu LG(傅立国).Rare&Endangered Plant in China(中国珍稀濒危植物).Shanghai:Shanghai Education Press,1989.353.
  • 2LiX(李祥) ChenJW(陈建伟) HuangYY(黄玉宇).Research of Radix Changii Preparata influencing on the co-agulation time and the platelet aggregation[J].中成药,1998,20:17-19.
  • 3HuaYL(华一利) ChenJW(陈建伟) WuHP(吴慧平) etal.Experimental study on the antihyperlipidemia effect ofRadix Changii[J].南京中医药大学学报,1994,10:31-32.
  • 4WuHP(吴慧平) HuaYL(华一利) XiPL(席蓓莉) etal.Antioxidation of Radix Changii in hypercholesterolemiarats[J].南京中医药大学学报,1994,10:33-34.
  • 5DuanZF(段志富) ChenJW(陈建伟) LiX(李祥) etal.Comparative study of phellopterin in different sites ofChangium smyrnioides Wolff[J].中成药,2008,30:1851-1853.
  • 6陈建伟,段志富,李祥,陈勇.明党参药材水溶性活性成分的研究[J].天然产物研究与开发,2010,22(2):232-234. 被引量:9
  • 7Kimura Y,Ohminami H,Arichi H,et al.Effects of variouscoumarins from roots of Angelica dahurica on actions ofadrenaline,ACTH and insulin in fat cell.Planta Med,1982,45:183-187.
  • 8Dekermendjian K,Ai J,Nielsen M,et al.Characterization ofthe furanocoumarin phellopterin as a rat brain benzodiazepinereceptor partial agonist in vitro.Neurosci Lett,1996,219:151-154.
  • 9Li HT,He L,Qiu JB.Effects of the Chinese herb componentphellopterin on the increase in cytosolic free calcium in PC12cells.Drug Dev Res,2007,68:78-83.
  • 10Ho PC,Saville DJ,Wanwimolruk S.Inhibition of human-CYP3A4 activity by grapefruit flavonoids,furanocoumarinsand related compounds.Pharm Pharm Sci,2001,4:217-227.

二级参考文献9

共引文献8

同被引文献96

引证文献6

二级引证文献36

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部