输配水材料浸泡水中3种双酚类化合物的固相萃取-液相色谱-质谱测定法

Determination of Three Kinds of Bisphenols in Soak Water of Plastic Materials for Drinking Water Supply System by Solid Phase Extraction-Liquid Chromatography-Tandem Mass Spectrometry

目的建立输配水材料浸泡水中双酚F(bisphenol F,BPF)、双酚A(bisphenol A,BPA)和四溴双酚A(2,2',6,6'-tetrabromobisphenol A,TBBPA)三种双酚类化合物的测定方法。方法将30件输配水材料样品在室温避光条件下超纯水浸泡(24±1)h后,取200 ml浸泡水于C18固相萃取柱进行净化浓缩,采用液相-色谱-质谱(LC-MS-MS)法测定双酚F、双酚A和四溴双酚A的浓度。结果双酚F、双酚A和四溴双酚A分别在0.027～333、0.032～333、0.006～333μg/L的线性范围内,所得回归方程均呈较好的线性关系(r≥0.999),检出限分别为8、10、2 ng/L,定量下限分别为27、32、6 ng/L。该方法所得的平均回收率为77.4%～117.0%,RSD为3.9%～17.0%。结论该方法灵敏度高,选择性强,适用于输配水材料浸泡水中双酚类化合物双酚F、双酚A和四溴双酚A的测定。

Objective To develop a method for the determination of bisphenol F,hisphenol A and tetrabromobisphenol A in soak water of the materials for drinking water supply system. Methods A total of 30 materials for drinking water supply system were leached at room temperature for （24±1） hours. 200 ml soak water were preconcentrated on C18 solid phase extraction cartridge,and bisphenol F,bisphen01 A and tetrabromobisphenol A were quantitatively analyzed by liquid chromatography tandem mass spectrometry （LC-MS-MS）method. Results The calibration curves of bisphenol F,bisphenol A and tetrabromobisphenol A showed a good linearity in the range of 0.027-333, 0.032-333 and 0.006-333 μg/L respectively, and the correlation coefficients were more than 0.999. The limits of quantification （LOQ）of bisphenol F,bisphenol A and tetrabromobisphenol A were 27, 32 and 6 ng/L respectively. The spiked recoveries ranged from 77.4% to 117.0% with the relative standard deviations of 3.9%-17.0%. Conclusion The method is sensitive,accurate,and applicable to the determination of bisphenol F,bisphenol A and tetrabromobisphenol A in soak water of the materials for drinking water supply system.