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儿童食物变态反应的发病机制及诊治进展 被引量：7

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摘要 近年儿童食物变态反应（foodallergy，FA）的发病率越来越高，逐渐引起儿科医师及患儿家长的重视。美国自1997年至2007年在小于18岁儿童中FA的发病率增幅达18％[1]。
作者 孙梅 郭静
机构地区 中国医科大学附属盛京医院儿科
出处 《中华妇幼临床医学杂志（电子版）》 CAS 2012年第2期93-96,共4页 Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
基金 中国高校博士点专项科研基金联合资助(20092104110010)
关键词 食物变态反应 发病机制 儿童 诊治 患儿家长 儿科医师 发病率
分类号 R725.9 [医药卫生—儿科]
  • 相关文献

参考文献16

  • 1Branum AM, Lukacs SL. Food allergy among children in the United States[J]. Pediatrics,2009, 124 : 1549-1555.
  • 2Dupont C. Food allergy: Recent advances in pathophysiology and diagnosis[J]. Ann Nutr Metab, 2011,59(Snppl 1):8-18.
  • 3Scurlock AM, Vickery BP, Hourihane JO, et al. Pediatric food allergy and mucosal tolerance[J]. Mucosal Immunol, 2010,3 (4) : 345-354.
  • 4Allen K, Martin PE. Clincal aspects of pediatric food allergy and failed oral immune tolerance[J]. J Clin Gastroenterol, 2010, 44 (6) :391-401.
  • 5Shreffler WG, Wanich N, Moloney M, et al. Association of allergen-specific regulatory T cells with the onset of clinical tolerance to milk protein[J]. J Allergy Clin Immunol, 2009,123 (1):43-52.
  • 6王永明,胡燕,黎海芪.T细胞在口服耐受和食物过敏中的作用[J].中国实用儿科杂志,2007,22(7):549-551. 被引量：4
  • 7del Giudice MM, Leonardi S, Maiello N, et al. Food allergy and probiotics in childhood[J]. J Clin Gastroenterol, 2010,44 (Suppl 1): S22-25.
  • 8Marschan E, Kuitunen M, Kukkonen K, et al. Probiotics in infancy induce protective immune profiles that are characteristic for chronic low-grade inflammation[J]. Clin Exp Allergy, 2008, 38 (4) :611-618.
  • 9Kuitunen M, Kukkonen K, Juntunen-Backman K, et al. Probiotics prevent IgE-associated allergy until age 5 years in cesarean-delivered children but not in the total cohort [J]. JAllergy Clin Immunol,2009, 123(2) :335-341.
  • 10婴儿过敏性疾病预防、诊断和治疗专家共识[J].中华儿科杂志,2009,47(11):835-838. 被引量：71

二级参考文献17

  • 1Calder PC.Dietary nucleic acids and Th1/Th2 balance:a clue to cow's milk allergy?[J].Clin Exp Allergy,2000,30(7):908-911.
  • 2Turcanu V,Maleki SJ,Lack G.Characterization of lymphocyte responses to peanuts in normal children,peanut-allergic children,and allergic children who acquired tolerance to peanuts[J].J Clin Invest,2003,111(7):1065-1072.
  • 3Satter MA,Sakai K,Ahmed S,et al.Low-protein diet induces oral tolerance to ovalbumin in mice[J].J Nutr Sci Vitaminol(Tokyo),2002,48(1):51-58.
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  • 6Perez-Machado MA,Ashwood P,Thomson MA,et al.Reduced transforming growth factor-betal-producing T cells in the duodenal mucosa of children with food allergy[J].Eur J Immunol,2003,33(8):2307-2315.
  • 7Rautava S,Isolaufi E.Cow's milk allergy in infants with atopic eczema is associated with aberrant production of intefleukin-4 during oral cow's milk challenge[J].J Pediatr Gastroenterol Nutr,2004,39(5):529-535.
  • 8Groux H,O Garra A,Bigler M,et al.A CD4^+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis[J].Nature,1997,389:737-742.
  • 9Chehade M,Mayer L.Oral tolerance and its relation to food hypemensitivities[J].J Allergy Clin Immunol,2005,115:3-12.
  • 10Tsuji NM,Mizumachi K,Kurisaki J.Interleukin-10-secreting Peyer's patch cells are responsible for active suppression in lowdose oral tolerance[J].Immunology,2001,103(4):458-64.

共引文献73

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二级引证文献88

中华妇幼临床医学杂志（电子版）
2012年 第2期

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