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干扰素联合拉米夫定治疗慢性乙型肝炎的临床分析 被引量:3

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摘要 目的观察干扰素联合拉米夫定治疗慢性乙型肝炎的临床效果。方法回顾性分析2007年12月~2010年9月住院治疗的60例慢性乙型肝炎患者的临床资料。结果治疗12个月时,60例患者血清HBV-DNA转阴者54例,阴转率为90.0%;血清HBeAg转阴者37例,阴转率约为61.7%;ALT恢复正常者56例,复常率约为93.3%;60例患者有8例(13.3%)发生HBeAg血清学转化。结论拉米夫定联合干扰素治疗慢性乙型肝炎疗效显著,值得临床推广应用。
作者 马爱玲
出处 《中国医药科学》 2012年第6期64-64,67,共2页 China Medicine And Pharmacy
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  • 1杨绍基,任红.传染病学[M].第7版.北京:人民卫生出版社,2010.
  • 2杨绍基,任红.传染病学[M].第七版.北京:人民卫生出版社,2010:1-15.
  • 3Chinese Society of Hepatology and Chinese Society of Infec- tious Diseases, Chinese Medical Association.The guideline of prevention and treatment for chronic hepatitis B(2010 version) [J]. Chin J Hepatol, 2011, (19) : 13-24.
  • 4杨宝峰.药理学[M].第7版.北京:人民卫生出版社,2012:430-431.
  • 5van Bmmel F, de Man RA, Wedemeyer H, et al. Long - term efficacy of tenofovir monotherapy for hepatitis B virus mono infected patients after failure of nueleoside/nucleotide analogues [J]. Hematology, 2010, 51 (1) : 73 -80.
  • 6Jayakumar R, Joshi YK, Singh S. Laboratory evaluation of three regi- mens of treatment of ehronie hepatitis B : tenofovir, endeavor and combi- nation of lamivudine and adenoviral [J]. J Lab Physicians, 2012, 4 (1): 10-16.
  • 7Lu JJ, Liu K, Ma Y J, et al. Efficacy and safety of telbivudine plus ad- enoviral dipivoxil combination therapy and endeavor immunotherapy for HBeAg - positive chronic hepatitis B patients with resistance to adenovi- raldipivoxil [J] .JViralHepat, 2013, 20 (1): 40-45.
  • 8Hagiwara S, Kudo M, Osaki Y, et al. Impact of peg interferon alpha -2b and endeavor hydrate combination therapy on persistent viral suppression in patients with chronic hepatitis B [J]. J Med Virol, 2013, 85 (6):987-995.
  • 9Mello Francisco Campello do Amaral,Fernandes Carlos Augusto,Gomes Selma de Andrade.Antiviral therapy against chronic hepatitis B in Brazil: high rates of lamivudine resistance mutations and correlation with HBV genotypes. Memórias do Instituto Oswaldo Cruz . 2012
  • 10Carey Ivana,D’Antiga Lorenzo,Bansal Sanjay,Longhi Maria Serena,Ma Yun,Mesa Irene Rebollo,Mieli-Vergani Giorgina,Vergani Diego.Immune and viral profile from tolerance to hepatitis B surface antigen clearance: a longitudinal study of vertically hepatitis B virus-infected children on combined therapy. Journal of Virology . 2010

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