期刊文献+

局部进展期低位直肠癌术前同步放化疗疗效观察

下载PDF
导出
摘要 目的:评价局部进展期低位直肠癌术前同步放化疗的疗效。方法:对30例局部进展期低位直肠癌患者放疗+同步口服希罗达,4~6周后行手术治疗。结果:全部患者均完成治疗。术后病理学完全缓解(CR)率为13.3%,保肛率为53.3%,1、2级毒性反应总发生率为70%,3、4级为16.7%。结论:对于局部进展期低位直肠癌患者术前同步放化疗安全有效,提高手术切除率、保肛率的同时,并未增加其毒副反应的发生。
出处 《北方药学》 2012年第4期44-44,共1页 Journal of North Pharmacy
  • 相关文献

参考文献4

二级参考文献14

  • 1施从先.热、放射诱导的SHG-44细胞凋亡与Fas/FasL、Caspase-3表达关系[J].江苏医药,2004,30(12):912-914. 被引量:3
  • 2增益新主编.肿瘤学.北京:人民卫生出版社,2000.143
  • 3Abdulkarim B,Sabris C,Deutsch E,et al.Radiation-induced expression of functional Fas ligand in EBV-positive human nasopharyngeal carcinoma cells.Int J Cancer,2000,86(3):229-237.
  • 4Kimura K,Gelmann EP.Tumour necrosis factor-alpha and Fas activate complementary Fas-associated death domain-dependent pathways that enhance apotosis induced by gama-irradiation.J Biol Chem,2000,275(9):8 610-8 622.
  • 5Hasegawn M,Yamakama M,Mitsuhashi N,et al.Immunohistochemical study of radioation-induced apoptosis and oncogehea.Nippon Igak Hoshasen Gakkai Zasshi,1995,55(4):779.
  • 6Wadler S.Systemic treatment of advanced colorectal cancer:Incorporating new agents into the therapentic strategy.Seminars Colon Rectal Surgery,2002,13(4):269-276.
  • 7Macurer CA,Borner M,Buchler MW.Regional chemotherapy of gastrointerstinal cancer.Digestive Surgery,1997,154(6):9-22.
  • 8Li WX,Ling CC.Apoptosis in heat-induced cell killing:the protective role of HSP-70 and sensitization effect of the c-myc gene.Radiates,1996,145(2):324-332.
  • 9Liu RY,Matsumoto K,Kunis hio K,et al.Proliferative potential and apoptosis in rat glioma cell lines after hyperthermia.Neurol Med Chir,1998,38(3):196-201.
  • 10J.B.DUBOIS,顾胜德,J.GARY-BOBO,C.L.SOLASSOL,H.PUJOL.直肠癌的术前放射治疗[J].中华放射肿瘤学杂志,1989(3):20-22. 被引量:7

共引文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部