不同剂量布比卡因腰硬联合麻醉对剖宫产产妇血液流变学影响比较

Comparison on the influence of different doses Bupivacaine combined with pinal-epidural anesthesia for hemorheology of parturient underwent caesarean section

目的比较不同剂量布比卡因腰硬联合麻醉对剖宫产产妇血液流变学的影响。方法选取2009年10月~2011年10月于本院进行采用腰硬联合麻醉进行剖宫产的84例产妇为研究对象,将其分为A组与B组,每组各42例。A组采用7.0 mg的0.75%布比卡因进行麻醉,B组采用9.0 mg的0.75%布比卡因进行麻醉,后将两组产妇不良反应发生率及麻醉前及麻醉后5、15、30 min的血液流变学指标进行检测及比较。结果 B组麻醉后5、15、30 min的各项血液流变学指标低于A组（均P〈0.05）,而两组患者不良反应发生率比较差异无统计学意义（P〉0.05）。结论 9.0 mg的0.75%布比卡因对剖宫产产妇的血液流变学影响更为明显,可显著改善产妇的血液循环状态,且安全性也较高,故更适用于剖宫产术。

Objective To compare the influence of different doses bupivacaine combined with spinal-epidural anesthesia for hemorheology of parturient underwent caesarean section.Methods 84 parturient underwent caesarean section with spinal-epidural anesthesia in our hospital from October 2009 to October 2011 were selected as research object,and they were divided into group A and group B with 42 cases in each group,the group A were given 7.0 mg 0.75% Bupivacaine,the group B were given 9.0 mg 0.75% Bupivacaine,then the incidence of adverse reactions and hemorheology indexes before and after the anesthesia at 5,15,30 min of two groups were detected and compared.Results The after the anesthesia at 5,15,30 min of group B were all lower than those of group A（all P〈0.05）,there were all significant differences,but the incidence of adverse reactions of two groups had no significant differences（P〈0.05）.Conclusion The influence of 9.0 mg 0.75% Bupivacaine for hemorheology of parturient underwent caesarean section is more obvious,and it can sig nificantly improve blood circulation status of parturient and the security is higher,so it is more suitable for cesarean section.