早发型重度子痫前期62例临床分析

Clinical analysis of 62 cases with early onset severe pre-eclampsia

目的探讨早发型重度子痫前期的处理方法及对围生期母婴预后的影响。方法回顾性分析2005年1月～2010年11月本院产科62例早发型重度子痫前期患者的临床资料,根据发病孕周分为A组(<28周)11例、B组(28～31+6周)30例,C组(32～33+6周)21例。结果 3组孕产妇并发症发生率比较差异无统计学意义(P>0.05);新生儿窒息率及围生儿死亡率随孕龄减小而升高(P<0.05),B组期待治疗时间明显长于A、C组(P<0.05),A、C组间比较差异无统计学意义(P>0.05)。结论对早发型重度子痫前期患者应严密监护母胎情况,并适时终止妊娠。

Objective To inverstigate the clinical treatment and the impact on the prognosis of perinatal mathers and in - fants of early onset severe pre-eclampsia. Methods Retrospective study was carried out on 62 patients with early onset severe pre-eclampsia from January 2005 to November 2010. They were divided into three groups according to gestational weeks： group A （28 weeks）, group B （28～31＋6 weeks） and group C （32～33＋6 weeks）. Results The incidence of complication was no significant difference among the three groups （P0.05）; The rates of neonatal asphyxia and perinatal mortality complications among these three groups was decrease with the increase of gestational （P 0.05）. The duration time of expectant treatment in group B was significantly longer than those in the other two groups （P 0.05）, but there was no significant difference among group A and group C （P0.05）. Conclusion It is necessary to monitor the conditions of the methers and fetuses close and adopt appropriate methods to teminate pregnancy.